2-(4-Methylphenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile CAS 478068-03-0
| CAS No. | 478068-03-0 |
| Molecular Formula | C18H11F3N2S |
| Molecular Weight | 344.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(4-Methylphenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 478068-03-0), a certified reference material (molecular formula C18H11F3N2S, MW 344.35 g/mol) for analytical method development and quality control.
Based on its molecular formula C18H11F3N2S, 2-(4-Methylphenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 344.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H11F3N2S |
| Molecular Weight | 344.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylphenyl Standards
- N-{[(4-methylphenyl)carbamoyl]amino}-3-(thiophen-2-yl)-4,5-dihydro-1,2-oxazole-5-carboxamide (CAS 478259-21-1)
- 1-{1-[(4-methylphenyl)methyl]-5-oxopyrrolidine-3-carbonyl}piperidine-4-carboxylic acid (CAS 1291861-89-6)
- 2-(4-Methylphenyl)-5-{4H,5H-naphtho[1,2-b]thiophen-2-yl}-1,3,4-oxadiazole (CAS 478033-55-5)
- 4-({4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl)morpholine (CAS 477860-51-8)
- 2-{[(4-methylphenyl)methyl]sulfanyl}-5-[(4-methylpiperazin-1-yl)methyl]-1,4-dihydropyrimidin-4-one (CAS 1221715-27-0)
- 2-(4-Methylphenyl)-5-{thieno[2,3-b]quinolin-2-yl}-1,3,4-oxadiazole (CAS 692260-13-2)
- 4-[(4-Methylphenyl)sulfanyl]-3-nitrobenzyl cyclopropanecarboxylate (CAS 320424-05-3)
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Recommended Standards
- 2-(2-(((3-(Furan-2-yl)-5-thioxo-1H-1,2,4-triazol-4(5H)-yl)imino)methyl)phenoxy)acetic acid (CAS 478253-70-2)
- 2,3'',4'',5''-Tetrafluoro-4-propyl-1,1':4',1''-terphenyl (CAS 205806-88-8)
- 1,1-Dioxido-2,3-dihydro-4H-thieno[2,3-b]thiopyran-4-yl 2,6-difluorobenzoate (CAS 343373-67-1)
- 4-(4-Ethylphenyl)-2-(ethylsulfonyl)-6-(trifluoromethyl)pyrimidine (CAS 862783-00-4)
- 4-Hydroxy-3-(methylthio)benzamide (CAS 110642-31-4)
- (2-((9,9-Dimethyl-9H-fluoren-2-yl)dimethylsilyl)phenyl)methanol (CAS 1244855-65-9)
- 1-(4-Fluorophenyl)-5-(methylthio)-3-phenyl-1H-pyrazole (CAS 871110-08-6)
- (3-Chlorophenyl)(3-(difluoromethoxy)phenyl)methanone (CAS 1712958-76-3)
- 3-(4-Methylbenzyl)pyrido[3,2-d]pyrimidine-2,4(1h,3H)-dione (CAS 919967-71-8)
- (S)-Methyl 2-(2-chloroacetamido)propanoate (CAS 118375-95-4)
- 4-Bromo-2-butoxypyridine (CAS 1289027-85-5)
- 3-Cyclopropyl-3-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS 683217-51-8)
- tert-Butyl 5-bromo-3,4-dihydro-2,6-naphthyridine-2(1H)-carboxylate (CAS 1393552-99-2)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
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