| CAS No. | 478076-86-7 |
| Molecular Formula | C18H18N4OS |
| Molecular Weight | 338.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
N'-[(1E)-[4-(Dimethylamino)phenyl]methylidene]-3-(1H-pyrrol-1-yl)thiophene-2-carbohydrazide (CAS 478076-86-7) is a high-purity analytical reference standard with the molecular formula C18H18N4OS and a molecular weight of 338.43 g/mol.
N'-[(1E)-[4-(Dimethylamino)phenyl]methylidene]-3-(1H-pyrrol-1-yl)thiophene-2-carbohydrazide (C18H18N4OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C18H18N4OS |
| Molecular Weight | 338.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |