2-(4-(3-(Trifluoromethyl)benzyl)piperazin-1-yl)benzo[d]thiazole CAS 478077-00-8
| CAS No. | 478077-00-8 |
| Molecular Formula | C19H18F3N3S |
| Molecular Weight | 377.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-(3-(Trifluoromethyl)benzyl)piperazin-1-yl)benzo[d]thiazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(4-(3-(Trifluoromethyl)benzyl)piperazin-1-yl)benzo[d]thiazole (CAS 478077-00-8), a certified reference material (molecular formula C19H18F3N3S, MW 377.43 g/mol) for analytical method development and quality control.
Structurally, 2-(4-(3-(Trifluoromethyl)benzyl)piperazin-1-yl)benzo[d]thiazole (C19H18F3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 377.43 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-(3-(Trifluoromethyl)benzyl)piperazin-1-yl)benzo[d]thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18F3N3S |
| Molecular Weight | 377.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- N-(4-{2-[3-(Trifluoromethyl)anilino]-1,3-thiazol-4-yl}phenyl)acetamide (CAS 1023875-75-3)
- 3-({[3-(trifluoromethyl)phenyl]sulfanyl}methyl)-1H,2H,3H,5H-imidazo[2,1-b]quinazolin-5-one (CAS 478032-74-5)
- Methyl 2-[({[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]carbamoyl}methyl)sulfanyl]benzoate (CAS 339013-90-0)
- 2-(2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamido)benzoic acid (CAS 692732-72-2)
- Methyl 2-(2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetamido)benzoate (CAS 383148-72-9)
- 3-(Trifluoromethyl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)benzenesulfonamide (CAS 339103-79-6)
- 1-(2-Methyl-3-(trifluoromethyl)phenyl)-3-(2-methyl-6-(trifluoromethyl)pyridin-3-yl)urea (CAS 2197055-55-1)
- 6-(Trifluoromethyl)-N'-(3-(trifluoromethyl)benzoyl)nicotinohydrazide (CAS 1092346-10-5)
Recommended Standards
- 2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azaspiro[3.4]octane-1-carboxylic acid (CAS 2137442-87-4)
- 2-(9h-Fluoren-9-ylmethoxycarbonyl)-2-azabicyclo[2.2.2]octane-3-carboxylicacid (CAS 2382870-02-0)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(spiro[3.3]heptan-2-yl)propanoic acid (CAS 2098113-94-9)
- 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-azabicyclo[2.2.2]octane-1-carboxylic Acid (CAS 1987261-87-9)
- Ruscogenin/Neoruscogenin mixture (CAS 50933-59-0)
- 5-(Piperidin-1-yl)pyridin-2-amine, 97% (CAS 94924-94-4)
- 4'-Chloro-[1,1'-biphenyl]-2,3'-dicarboxylic acid 2-methyl ester (CAS 878207-35-3)
- tert-Butyl 1,8-diazaspiro[3.6]decane-8-carboxylate (CAS 1251020-63-9)
- 2-(2-Bromoethyl)morpholine (CAS 2169435-76-9)
- 2-(4-Chlorophenyl)-9,12-dioxa-1,2,4-triazadispiro[4.2.4(8).2(5)]Tetradecan-3-one (CAS 338956-26-6)
- 3-amino-2-[(3,4-difluorophenyl)methyl]propanamide (CAS 1038293-42-3)
- 6,7-Dimethoxyquinoline-4-thiol (CAS 35654-48-9)
- 2-(4-Methoxyphenyl)cyclobutan-1-ol (CAS 1315366-93-8)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
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