1-(4-Methoxybenzenesulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine CAS 478077-41-7
| CAS No. | 478077-41-7 |
| Molecular Formula | C17H18F3N3O3S |
| Molecular Weight | 401.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-Methoxybenzenesulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-Methoxybenzenesulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine (CAS 478077-41-7) is a high-purity analytical reference standard with the molecular formula C17H18F3N3O3S and a molecular weight of 401.40 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(4-Methoxybenzenesulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 401.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(4-Methoxybenzenesulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18F3N3O3S |
| Molecular Weight | 401.40 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methoxybenzenesulfonyl Standards
- 1-(4-Methoxybenzenesulfonyl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine (CAS 478077-45-1)
- 1-(4-Methoxybenzenesulfonyl)-8'-methyl-3',4'-dihydro-1'h-spiro[piperidine-4,2'-quinazoline]-4'-one (CAS 1049632-18-9)
- 5-[1-(4-Methoxybenzenesulfonyl)-1H-pyrazol-3-yl]-2-phenyl-1,3-thiazole (CAS 318248-78-1)
- 5-(4-Methoxybenzenesulfonyl)-8-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 860786-88-5)
- Ethyl 2-[1-(4-methoxybenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-2-oxoacetate (CAS 860612-17-5)
- 4-(4-Methoxybenzenesulfonyl)-3-phenyl-3,4-dihydro-2H-1,4-benzoxazine (CAS 338962-42-8)
- Ethyl 4-(4-methoxybenzenesulfonyl)-1-[(4-methylphenyl)methyl]piperidine-4-carboxylate (CAS 212770-64-4)
- (2S)-2-{[1-(4-methoxybenzenesulfonyl)piperidin-4-yl]formamido}propanoic acid (CAS 1212420-14-8)
Recommended Standards
- 1-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4,4-difluorocyclohexane-1-carboxylic acid (CAS 1986905-26-3)
- (S)-2-(1-(9H-Purin-6-ylamino)ethyl)-5-fluoro-3-phenylquinazolin-4(3H)-one (CAS 870281-17-7)
- 1-Methyl-3-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-thieno[2,3-c]pyrazole-5-carboxamide (CAS 478066-99-8)
- Deracoxib-d4 (CAS 1794780-24-7)
- (R)-1-amino-1-(3-fluoro-4-(trifluoromethyl)phenyl)-2-methylpropan-2-ol (CAS 2222681-45-8)
- Alloferon 1 (CAS 347884-61-1)
- 2-Bromo-4-nitrothiazole (CAS 41731-79-7)
- 4-(4-Fluorophenyl)-2-oxo-2,5-dihydrofuran-3-carbonitrile (CAS 50691-04-8)
- Moxidectin EP Impurity C (CAS 114041-23-5)
- 3-[(tert-butyldimethylsilyl)oxy]-3-cyclohexylbutanal (CAS 2044927-01-5)
- 3-(fluoromethyl)azetidin-3-ol (CAS 2167887-55-8)
- 3-Chloro-2-hydroxyphenacyl bromide (CAS 84320-78-5)
- (1-Methyl-5-(trifluoromethyl)-1H-pyrrol-2-yl)methanamine hydrochloride (CAS 1823245-64-2)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
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