3-{4-[(4-Fluorophenyl)sulfonyl]piperazino}-6-phenylpyridazine CAS 478077-49-5
| CAS No. | 478077-49-5 |
| Molecular Formula | C20H19FN4O2S |
| Molecular Weight | 398.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-{4-[(4-Fluorophenyl)sulfonyl]piperazino}-6-phenylpyridazine is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-{4-[(4-Fluorophenyl)sulfonyl]piperazino}-6-phenylpyridazine (CAS 478077-49-5), molecular formula C20H19FN4O2S and molecular weight 398.45 g/mol, is a CATO reference standard with documented purity and traceability.
3-{4-[(4-Fluorophenyl)sulfonyl]piperazino}-6-phenylpyridazine (C20H19FN4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-{4-[(4-Fluorophenyl)sulfonyl]piperazino}-6-phenylpyridazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H19FN4O2S |
| Molecular Weight | 398.45 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- methyl 8-(3-{[(4-fluorophenyl)sulphonyl]methyl}-1,2,4-oxadiazol-5-yl)octanoate (CAS 680215-96-7)
- (E)-3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-N-(pyridin-3-ylmethyl)acrylamide (CAS 956691-12-6)
- N-(1-((4-Fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)ethanesulfonamide (CAS 941882-72-0)
- N-(3-((2-Fluorophenyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazole-4-sulfonamide (CAS 1798530-41-2)
- 1-(3-Fluorophenyl)-2-(triphenylphosphoranylidene)ethanone (CAS 61748-01-4)
- 4,6-Bis(4-fluorophenyl)-2-methyl-5-(pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridine (CAS 755753-89-0)
- N-(3-fluorophenyl)-2-((5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 557067-86-4)
- 4-(3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl)-2-(m-tolyl)phthalazin-1(2H)-one (CAS 1291862-08-2)
Recommended Standards
- 3,9-Di-tert-butyl 6-methyl 7-oxo-3,9-diazabicyclo[3.3.1]nonane-3,6,9-tricarboxylate (CAS 878002-62-1)
- 4-Methoxyphenyl 4-((6-(acryloyloxy)hexyl)oxy)benzoate (CAS 82200-53-1)
- 3,4-Bis(4-methoxyphenyl)-1-(2-methylbenzoyl)-1H-pyrazole (CAS 956796-38-6)
- 4-Methyl-5-(3-(thiophen-2-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 477854-06-1)
- 6-Chloro-2,5-dimethylpyrimidin-4(1H)-one (CAS 1194-73-6)
- Ethyl (2Z)-2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-enoate (CAS 338966-65-7)
- 5-MEthanesulfonyl-1,3-benzoxazol-2-amine (CAS 1507862-91-0)
- N-(methylsulfonyl)-N-(2,4,5-trichlorophenyl)glycine (CAS 714260-75-0)
- (2-(3-Methoxypropoxy)phenyl)boronic acid (CAS 1122568-12-0)
- 4-(5-Chloro-2-methoxyphenyl)butan-2-amine (CAS 943116-71-0)
- 2,3-Dibromo-5-fluoroacetophenone (CAS 1806294-60-9)
- 2-(Bromomethyl)-4-methoxy-1-(trifluoromethyl)benzene (CAS 1261682-10-3)
- 1-([1,1'-biphenyl]-3-yl(phenyl)methyl)-1H-imidazole (CAS CATO-C3D-26005)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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