(E)-3-(1,3-Benzodioxol-5-yl)-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-propen-1-one CAS 478079-14-0

Purity 97%+In StockPharmaceutical Standards
CAS No.478079-14-0
Molecular FormulaC20H15NO3S
Molecular Weight349.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-3-(1,3-Benzodioxol-5-yl)-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-propen-1-one CAS 478079-14-0 chemical structure

Description

(E)-3-(1,3-Benzodioxol-5-yl)-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-propen-1-one (CAS 478079-14-0) is a high-purity analytical reference standard with the molecular formula C20H15NO3S and a molecular weight of 349.40 g/mol.

The molecular framework of (E)-3-(1,3-Benzodioxol-5-yl)-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-propen-1-one (C20H15NO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC20H15NO3S
Molecular Weight349.40 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1
Sulfur Atoms1

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