3-Chloro-N-(4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)-3-fluorophenyl)benzamide CAS 478079-25-3
| CAS No. | 478079-25-3 |
| Molecular Formula | C23H20Cl2FN3O3S |
| Molecular Weight | 508.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-N-(4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)-3-fluorophenyl)benzamide (CAS 478079-25-3), molecular formula C23H20Cl2FN3O3S and molecular weight 508.39 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chloro-N-(4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)-3-fluorophenyl)benzamide (C23H20Cl2FN3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H20Cl2FN3O3S |
| Molecular Weight | 508.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Span 20 (CAS 1338-39-2)
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- 1-Benzhydryl-3-fluoroazetidine-3-carbonitrile (CAS 1421920-56-0)
- N-(4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)-1H-imidazole-1-carboxamide (CAS 1357476-70-0)
- 2-(Chloromethyl)-5-ethoxybenzo[d]oxazole (CAS 1803795-06-3)
- (S)-tert-Butyl ethyl(1-(2-hydroxyethyl)pyrrolidin-3-yl)carbamate (CAS 1354003-22-7)
- 3-((3-Fluorobenzyl)thio)-1-(o-tolyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 439096-94-3)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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