3-(2-Pyridinyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid CAS 478080-12-5
| CAS No. | 478080-12-5 |
| Molecular Formula | C14H7F3N2O2S |
| Molecular Weight | 324.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Pyridinyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid (CAS 478080-12-5) is a high-purity analytical reference standard with the molecular formula C14H7F3N2O2S and a molecular weight of 324.28 g/mol.
Structurally, 3-(2-Pyridinyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid (C14H7F3N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 324.28 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(2-Pyridinyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H7F3N2O2S |
| Molecular Weight | 324.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Pyridinyl Standards
- 3-(3-Pyridinyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid (CAS 339099-38-6)
- 1-(4-Pyridinyl)-1-ethanone N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazone (CAS 551921-12-1)
- 2-[(1-(2-pyridinylÂ)-ethylÂ)sulfoÂ]-5-methylÂbenzÂimidazole (CAS 69417-07-8)
- 5-Methyl-2-(2-pyridinyl)-1,3-thiazol-4-yl 2,4-difluorobenzenecarboxylate (CAS 338399-07-8)
- 5-Methyl-2-(4-pyridinyl)-1,3-thiazol-4-yl 2,4-difluorobenzenecarboxylate (CAS 338398-93-9)
- 1-(4-Pyridinyl)-1-ethanone N-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]hydrazone (CAS 339111-84-1)
- 2-(2-(2-(3-Pyridinyl)-1,3-thiazol-4-yl)-ethyl)-1H-isoindole-1,3(2H)-dione (CAS 860785-67-7)
- 1-(6-Methyl-2-pyridinyl)-N-[(Z)-2-thienylmethylidene]-1H-imidazole-4-carbohydrazide (CAS 477858-62-1)
Recommended Standards
- 2,3,6,7,10,11-Hexahydroxytriphenylene (CAS 4877-80-9)
- 1,6-Anhydro-4-O-alpha-D-glucopyranosyl-D-glucopyranose (CAS 2672-63-1)
- 4-((4-Nitrophenyl)carbamoyl)benzene-1-sulfonyl fluoride (CAS 740-61-4)
- 1,4-Benzenedicarboxylic acid, polymer with 1,2-ethanediol and .alpha.-hydro-.omega.-hydroxypoly(oxy-1,2-ethanediyl) (CAS 9016-88-0)
- 2-(3,4-Dichlorophenyl)-3-hydroxyacrylonitrile (CAS 77186-41-5)
- 4-Aminoadamantane-1-carboxylic acid hydrochloride (CAS 1245645-93-5)
- meso-Tetra(2-nitrophenyl) porphine (CAS 37116-82-8)
- 2-{[(3-chlorophenyl)methyl]sulfanyl}-4-(4-methylphenyl)-1H,4H,5H-indeno[1,2-d]pyrimidin-5-one (CAS 383147-82-8)
- (5-Chloro-2-fluorophenyl)(piperazin-1-yl)methanone (CAS 926238-77-9)
- 4-dimethylaminocinnamic acid (CAS 1552-96-1)
- YM348 (CAS 372163-84-3)
- Ethyl 2-(2-methyl-1-oxo-6-(((trifluoromethyl)sulfonyl)oxy)-1,2,3,4-tetrahydronaphthalen-2-yl)acetate (CAS 1414797-86-6)
- N-(2,3-Dihydro-1H-inden-2-yl)indoline-1-carbothioamide (CAS 391876-11-2)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
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