4-(4-Chlorophenyl)-2-(cyclopropylamino)nicotinonitrile CAS 478245-77-1
| CAS No. | 478245-77-1 |
| Molecular Formula | C15H12ClN3 |
| Molecular Weight | 269.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(4-Chlorophenyl)-2-(cyclopropylamino)nicotinonitrile (CAS 478245-77-1) is a high-purity analytical reference standard with the molecular formula C15H12ClN3 and a molecular weight of 269.73 g/mol.
4-(4-Chlorophenyl)-2-(cyclopropylamino)nicotinonitrile (C15H12ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 4-(4-Chlorophenyl)-2-(cyclopropylamino)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12ClN3 |
| Molecular Weight | 269.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
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- 3-(4-Chlorophenyl)-2-methylisoquinolin-1(2H)-one (CAS 142338-11-2)
- 3-(3-Chlorophenyl)-2-methylisoquinolin-1(2H)-one (CAS 188674-77-3)
- 3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-5-amine (CAS 19652-14-3)
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- (4-Chlorophenyl)(isoquinolin-1-yl)methanol (CAS 31101-09-4)
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Recommended Standards
- 4-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-5-amine (CAS 261761-14-2)
- 4-(4-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile (CAS 67438-99-7)
- 4-(3-Chlorophenyl)-1-phenyl-1H-pyrazol-5-amine (CAS 324008-92-6)
- 4-(4-Chlorophenyl)-3-methyl-5-phenyl-4H-1,2,4-triazole (CAS 90959-48-1)
- 7-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(2,2,2-trichloro-1-hydroxyethyl)heptanamide (CAS 1803571-70-1)
- 3-Amino-5-bromobenzofuran-2-carboxylic acid (CAS 1780197-72-9)
- SN-38-d3 Glucuronide (CAS CATO-C4X-15717)
- 3-(6-methylheptan-2-yl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 855715-17-2)
- 5-Bromo-4-hydroxypyridin-2(1H)-one (CAS 80791-79-3)
- 1-(Pyrazin-2-yl)piperidin-3-amine dihydrochloride (CAS 1332529-43-7)
- (S)-Ethyl 2-amino-3-phenylpropanoate (CAS 3081-24-1)
- 1-[2-(Benzylsulfanyl)ethyl]-3-(2-methylcyclohexyl)urea (CAS 1007818-44-1)
- [(5-Nitro-1H-benzimidazol-2-yl)thio]acetic acid (CAS 19951-24-7)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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