(E)-N'-(3,4-dimethoxybenzylidene)-3-((4-fluorobenzyl)oxy)thiophene-2-carbohydrazide CAS 478246-40-1
| CAS No. | 478246-40-1 |
| Molecular Formula | C21H19FN2O4S |
| Molecular Weight | 414.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-N'-(3,4-dimethoxybenzylidene)-3-((4-fluorobenzyl)oxy)thiophene-2-carbohydrazide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (E)-N'-(3,4-dimethoxybenzylidene)-3-((4-fluorobenzyl)oxy)thiophene-2-carbohydrazide (CAS 478246-40-1), a certified reference material (molecular formula C21H19FN2O4S, MW 414.45 g/mol) for analytical method development and quality control.
Based on its molecular formula C21H19FN2O4S, (E)-N'-(3,4-dimethoxybenzylidene)-3-((4-fluorobenzyl)oxy)thiophene-2-carbohydrazide contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 414.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-N'-(3,4-dimethoxybenzylidene)-3-((4-fluorobenzyl)oxy)thiophene-2-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19FN2O4S |
| Molecular Weight | 414.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- (E)-3-((2,5-dimethoxyphenyl)amino)-1-(3-(m-tolyl)benzo[c]isoxazol-5-yl)prop-2-en-1-one (CAS 691870-05-0)
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