4-[(3-Methoxyphenyl)sulfanyl]-2-[(4-methylphenyl)methanesulfonyl]-5,6,7,8-tetrahydroquinazoline CAS 478246-75-2
| CAS No. | 478246-75-2 |
| Molecular Formula | C23H24N2O3S2 |
| Molecular Weight | 440.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[(3-Methoxyphenyl)sulfanyl]-2-[(4-methylphenyl)methanesulfonyl]-5,6,7,8-tetrahydroquinazoline (CAS 478246-75-2), molecular formula C23H24N2O3S2 and molecular weight 440.58 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-[(3-Methoxyphenyl)sulfanyl]-2-[(4-methylphenyl)methanesulfonyl]-5,6,7,8-tetrahydroquinazoline (C23H24N2O3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 440.58 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H24N2O3S2 |
| Molecular Weight | 440.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methoxyphenyl Standards
- 2-((4-Methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide (CAS 1092829-79-2)
- 3-(2-Methoxyphenyl)-1-phenylprop-2-en-1-one (CAS 5416-70-6)
- 5-(4-Methoxyphenyl)isoxazol-3-amine (CAS 6525-97-9)
- (3Z)-2-{[(4-methoxyphenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478044-02-9)
- 2-((N-(2-Methoxyphenyl)-4-methylphenyl)sulfonamido)-N-(4-methoxypyridin-3-yl)acetamide (CAS 1890208-58-8)
- 4-Methoxyphenyl 3-O-Allyl-2-azido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside (CAS 889453-83-2)
- 4-Methoxyphenyl 3-O-allyl-2-azido-4-6-O-benzylidene-2-deoxy-β-D-glucopyranoside (CAS 889453-78-5)
- N-(2-Methoxyphenyl)-4-(3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanamido)benzamide (CAS 869474-43-1)
Recommended Standards
- 4-(3,4-Dimethoxyphenethyl)-5-(1-(ethylsulfonyl)piperidin-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 932807-05-1)
- AEE 788 (CAS 497839-62-0)
- 1,2-Bis(6,7-dimethoxy-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethane (CAS 486-49-7)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((5,6-dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 761420-54-6)
- 2-(3,5-Difluorophenyl)-1,3,4-oxadiazole (CAS 1171930-36-1)
- 2-Methoxy-[1,1'-biphenyl]-4-carbaldehyde (CAS 248263-04-9)
- 6-Methyl-5-(morpholin-4-yl)-3-[3-(trifluoromethyl)phenyl]-1,2,4-triazine (CAS 339103-67-2)
- 2-Ethyl-5-mercapto-6-propyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one (CAS 832740-57-5)
- 4-Amino-1-(2-methoxyethyl)-1,2-dihydropyridin-2-one hydrochloride (CAS 2126163-36-6)
- 1,4-Di(1,3-dioxolan-2-yl)butane (CAS 6543-02-8)
- 2-(4-iodo-1H-1,2,3-triazol-1-yl)acetic acid (CAS 1360607-69-7)
- Ethyl 6-(2,2,2-trifluoroethoxy)nicotinate (CAS 1263276-73-8)
- (T-4)-[1,1′-(1,2-Ethanediyl)bis[1,1-diphenylphosphine-κP]]diiodocobalt (CAS 34775-39-8)
- Des-Leu26-Tirzepatide (CAS CATO-CPTD788947)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com