5-(4-Methylbenzenesulfonyl)-4-(4-methylpiperazin-1-yl)-2-phenylpyrimidine CAS 478247-33-5
| CAS No. | 478247-33-5 |
| Molecular Formula | C22H24N4O2S |
| Molecular Weight | 408.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Methylbenzenesulfonyl)-4-(4-methylpiperazin-1-yl)-2-phenylpyrimidine (CAS 478247-33-5) is a high-purity analytical reference standard with the molecular formula C22H24N4O2S and a molecular weight of 408.52 g/mol.
The molecular framework of 5-(4-Methylbenzenesulfonyl)-4-(4-methylpiperazin-1-yl)-2-phenylpyrimidine (C22H24N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(4-Methylbenzenesulfonyl)-4-(4-methylpiperazin-1-yl)-2-phenylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24N4O2S |
| Molecular Weight | 408.52 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methylbenzenesulfonyl Standards
- 4-[4-Methyl-3-(4-methylbenzenesulfonyl)-6-phenylpyridin-2-yl]morpholine (CAS 478245-28-2)
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- (3Z)-3-{[1-(4-methylbenzenesulfonyl)-1H-indol-3-yl]methylidene}-2,3-dihydro-1H-indol-2-one (CAS 694437-74-6)
- 1-(4-Methylbenzenesulfonyl)-3-[(5-methylthiophen-2-yl)methyl]-3-(pyrazin-2-yl)urea (CAS 866154-01-0)
- 5-(4-Methylbenzenesulfonyl)-4-phenoxy-2-phenylpyrimidine (CAS 478080-84-1)
- Methyl 4-(4-methylbenzenesulfonyl)-3-(thiophene-2-amido)benzoate (CAS 477858-89-2)
- Methyl 4-[4-(4-methylbenzenesulfonyl)piperazin-1-yl]-3-nitrobenzoate (CAS 220110-87-2)
- 1-(4-Methylbenzenesulfonyl)pyrrolidin-3-yl 4-methylbenzene-1-sulfonate (CAS 131912-34-0)
Recommended Standards
- 5-((2,5-Dimethylbenzyl)thio)-2-ethyl-8,9-dimethoxy-[1,2,4]triazolo[1,5-c]quinazoline (CAS 860650-31-3)
- 8-(Butylthio)-1,3-dimethyl-7-(naphthalen-1-ylmethyl)-1H-purine-2,6(3H,7H)-dione (CAS 476480-86-1)
- 3'-(Benzenesulfonyl)-1'-[3-(1H-imidazol-1-yl)propyl]-4',5'-dimethyl-1'H-1,2'-bipyrrole (CAS 860648-67-5)
- 8,9-Dimethoxy-2-methyl-5-((2,4,6-trimethylbenzyl)thio)-[1,2,4]triazolo[1,5-c]quinazoline (CAS 860611-29-6)
- 2-(Benzyloxy)-5-fluoropyridin-3-ylboronic acid (CAS 1206776-48-8)
- 1-Methyl-3-[(prop-2-en-1-yl)amino]pyrrolidin-2-one (CAS 1343805-37-7)
- (E)-3-(p-Tolyl)prop-2-en-1-ol (CAS 122058-30-4)
- Miglitol Nitric Oxide (CAS CATO-C4X-16971)
- Cisatracurium Besilate EP Impurity D 3/2 Besylate (CAS CATO-C4X-185093)
- 3-((4-(Thiophen-2-yl)thiazol-2-yl)amino)benzoic acid (CAS 103755-01-7)
- 3-amino-4-(cyclopropylamino)benzonitrile (CAS 918152-17-7)
- spiro[3.3]heptan-2-one (CAS 30152-57-9)
- 7-Methoxy-2,2-dimethylchroman-4-one (CAS 20321-73-7)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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