2-(Methylthio)-5-(phenylsulfonyl)pyrimidin-4(3H)-one CAS 478247-40-4
| CAS No. | 478247-40-4 |
| Molecular Formula | C11H10N2O3S2 |
| Molecular Weight | 282.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Methylthio)-5-(phenylsulfonyl)pyrimidin-4(3H)-one (CAS 478247-40-4), a certified reference material (molecular formula C11H10N2O3S2, MW 282.34 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 2-(Methylthio)-5-(phenylsulfonyl)pyrimidin-4(3H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 282.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10N2O3S2 |
| Molecular Weight | 282.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methylthio Standards
- 3-Benzyl-2-(methylthio)quinazolin-4(3H)-one (CAS 1688-81-9)
- 5-(Methylthio)-3-(4-phenoxyphenyl)-1H-pyrazole (CAS 671754-10-2)
- 3-Methyl-2-(methylthio)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-4(3H)-one (CAS 1628606-29-0)
- ethyl 2-(methylthio)-4-(piperidin-1-yl)pyrimidine-5-carboxylate (CAS 100451-24-9)
- 5-Boc-2-(methylthio)-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidine (CAS 1246471-43-1)
- ethyl 2-(methylthio)-4-morpholinopyrimidine-5-carboxylate (CAS 100318-76-1)
- Ethyl 2-(methylthio)-4,5-dioxo-1,4,5,8-tetrahydropyrido[2,3-d]pyrimidine-6-carboxylate (CAS 34259-36-4)
- (3-{[(Methylthio)carbonyl]amino}-1-adamantyl)-acetic acid (CAS 864411-39-2)
Recommended Standards
- 2-(9H-Fluoren-9-ylidene)-1-phenylethanone (CAS 5653-33-8)
- 2,2'-Dinaphthyl ketone (CAS 613-56-9)
- 2-(4-Cyclohexyl-2,3-dioxopiperazin-1-yl)butanoic acid (CAS 951464-86-1)
- 2,6-Di(pyridin-4-yl)naphthalene (CAS 950520-39-5)
- 2-(hydroxymethyl)cyclobutan-1-one (CAS 23107-52-0)
- octa-3,5-diyne-1,8-diol (CAS 15808-23-8)
- 1-(4-Bromo-3-nitrophenyl)propan-1-one (CAS 101860-83-7)
- Crotonoside (CAS 1818-71-9)
- 6-Bromo-2-(methylsulfanyl)-3,4-dihydroquinazolin-4-one (CAS 174313-65-6)
- 3-(2,2-Dibromoethenyl)thiophene (CAS 81294-09-9)
- Methyl 2-((5,6-dimethyl-2H-pyran-2-yl)(ethoxy)amino)-5-((4-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505096-14-0)
- 5-(2-Fluorophenyl)-6-(trifluoromethyl)pyridin-2-ol (CAS 1214390-84-7)
- N-(2,4-Dibromophenyl)-4-methoxybenzamide (CAS 541545-55-5)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com