1-(2,4-Dichlorobenzyl)-3-(4-fluorobenzyl)-4-hydroxypyridin-2(1H)-one CAS 478247-91-5
| CAS No. | 478247-91-5 |
| Molecular Formula | C19H14Cl2FNO2 |
| Molecular Weight | 378.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 378.22 g/mol gives 1-(2,4-Dichlorobenzyl)-3-(4-fluorobenzyl)-4-hydroxypyridin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(2,4-Dichlorobenzyl)-3-(4-fluorobenzyl)-4-hydroxypyridin-2(1H)-one (CAS 478247-91-5) is a high-purity analytical reference standard with the molecular formula C19H14Cl2FNO2 and a molecular weight of 378.22 g/mol.
The molecular framework of 1-(2,4-Dichlorobenzyl)-3-(4-fluorobenzyl)-4-hydroxypyridin-2(1H)-one (C19H14Cl2FNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(2,4-Dichlorobenzyl)-3-(4-fluorobenzyl)-4-hydroxypyridin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14Cl2FNO2 |
| Molecular Weight | 378.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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