4-Fluoro-N'-(1-(phenylsulfonyl)piperidin-4-ylidene)benzohydrazide CAS 478248-21-4

Purity 97%+In StockPharmaceutical Standards
CAS No.478248-21-4
Molecular FormulaC18H18FN3O3S
Molecular Weight375.42 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Fluoro-N'-(1-(phenylsulfonyl)piperidin-4-ylidene)benzohydrazide CAS 478248-21-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-Fluoro-N'-(1-(phenylsulfonyl)piperidin-4-ylidene)benzohydrazide (CAS 478248-21-4), molecular formula C18H18FN3O3S and molecular weight 375.42 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Fluoro-N'-(1-(phenylsulfonyl)piperidin-4-ylidene)benzohydrazide (C18H18FN3O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), 4-Fluoro-N'-(1-(phenylsulfonyl)piperidin-4-ylidene)benzohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H18FN3O3S
Molecular Weight375.42 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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