5-(4-Chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}-2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine CAS 478248-95-2
| CAS No. | 478248-95-2 |
| Molecular Formula | C33H25ClF4N2S |
| Molecular Weight | 593.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-Chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}-2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine.
CATO supplies 5-(4-Chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}-2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine (CAS 478248-95-2), a certified reference material (molecular formula C33H25ClF4N2S, MW 593.08 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4-Chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}-2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine (C33H25ClF4N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C33H25ClF4N2S |
| Molecular Weight | 593.08 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- (E)-{[1-(4-chlorophenyl)-4-[(4-methylphenyl)sulfanyl]-2-phenyl-6,7-dihydro-1H-indol-5-yl]methylidene}amino 4-fluorobenzoate (CAS 477887-83-5)
- (3-Chlorophenyl)(phenyl)sulfane (CAS 40541-07-9)
- 2-((6-(4-Chlorophenyl)-3-cyano-4-(3,4-dimethoxyphenyl)pyridin-2-yl)thio)-N-(4-methoxy-2-nitrophenyl)acetamide (CAS 332127-47-6)
- (E)-(1-{4-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]phenyl}ethylidene)amino 3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 937604-54-1)
- (E)-{[1-(4-chlorophenyl)-4-[(4-methylphenyl)sulfanyl]-2-phenyl-6,7-dihydro-1H-indol-5-yl]methylidene}amino 3-methylbenzoate (CAS 478033-27-1)
- (E)-{[1-(4-chlorophenyl)-4-[(4-methylphenyl)sulfanyl]-2-phenyl-6,7-dihydro-1H-indol-5-yl]methylidene}amino 4-methylbenzoate (CAS 477887-84-6)
- Tris(3-chlorophenyl)(hexadecyl)silane (CAS 18759-06-3)
- Tris(4-chlorophenyl)(hexadecyl)silane (CAS 18759-07-4)
Recommended Standards
- 4-(5-(Benzylthio)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)-1-((4-chlorophenyl)sulfonyl)piperidine (CAS 478042-34-1)
- 1,2-Bis(3-(dodecylthio)thiophen-2-yl)ethene (CAS 1235883-28-9)
- 142761-78-2 (3-Ethynyl-4-{[tri(propan-2-yl)silyl]ethynyl}hex-3-ene-1,5-diyne-1,6-diyl)bis[tri(propan-2-yl)silane] DTXSID90565714 (CAS 142761-78-2)
- Arachidyl Arachidate (CAS 22432-80-0)
- 6-((1,2-Dihydroxyethoxy)methyl)-9-methoxyphenazine-1-carboxylic acid (CAS 2072-68-6)
- 4-Bromo-5-fluoro-2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxylic acid (CAS 2748790-08-9)
- 3-(2-Methoxyphenyl)thiophene-2-carboxylic acid (CAS 666841-74-3)
- 5-METHOXYINDOLINE HCL (CAS 4770-39-2)
- (11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-di-1-pyrenyl-4-oxide-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin (CAS 1225195-02-7)
- Methyl 3-(2-Methoxyphenyl)-3-oxopropanoate (CAS 54177-02-5)
- 4-Amino-8-methylthiochroman 1,1-dioxide (CAS 1184534-31-3)
- 3-(5-tert-Butyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride (CAS 1393330-46-5)
- 5-{[(4-methylphenyl)methyl]amino}-2,3-dihydro-1h-1,3-benzodiazol-2-one (CAS 393127-30-5)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com