1-Benzyl-4-(5-chloro-2-nitrobenzoyl)piperazine CAS 478249-18-2
| CAS No. | 478249-18-2 |
| Molecular Formula | C18H18ClN3O3 |
| Molecular Weight | 359.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Benzyl-4-(5-chloro-2-nitrobenzoyl)piperazine.
1-Benzyl-4-(5-chloro-2-nitrobenzoyl)piperazine (CAS 478249-18-2), molecular formula C18H18ClN3O3 and molecular weight 359.81 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-Benzyl-4-(5-chloro-2-nitrobenzoyl)piperazine (C18H18ClN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 359.81 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-Benzyl-4-(5-chloro-2-nitrobenzoyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O3 |
| Molecular Weight | 359.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Benzyl Standards
- (3-Chloro-4-methylphenyl)(4-(4-nitrophenyl)piperazin-1-yl)methanone (CAS 431996-53-1)
- (E)-6-Chloro-3-(pyridin-2-yl)-2-styrylquinazolin-4(3H)-one (CAS 708212-97-9)
- 1-{[6-Chloro-2-(furan-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 904818-06-0)
- 5-((2-Chloro-6-fluorobenzyl)thio)imidazo[1,2-c]quinazolin-2(3H)-one (CAS 478046-17-2)
- N-(3-chloro-2-(piperidin-1-yl)phenyl)-3-nitrobenzamide (CAS 383145-58-2)
- Benzyl (4-(3-chloro-5-ethynyl-4-fluorophenyl)butyl)carbamate (CAS 1427039-32-4)
- (E)-2-(2-chloro-6-fluorobenzyl)-5-(dimethylamino)-1-phenylpent-4-ene-1,3-dione (CAS 900015-47-6)
- 5-Chloro-N-(2-((3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl)phenyl)thiophene-2-carboxamide (CAS 1797962-38-9)
Recommended Standards
- 2-([1,1'-Biphenyl]-4-yl)-6-chloroquinoline-4-carboxylic acid (CAS 627907-09-9)
- 1-(4-Nitrophenyl)piperidin-4-one O-(4-chlorobenzyl) oxime (CAS 338757-93-0)
- 2-(4-Chlorobenzyl)-4-(2,4-dimethoxyphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861206-39-5)
- 1-(4-Chlorophenyl)-3-(4-(morpholine-4-carbonyl)phenyl)urea (CAS 496032-51-0)
- 1-(3,5-Dimethoxyphenyl)-4-methoxy-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (CAS 1616500-54-9)
- 1,3-Dibromo-5,7-bis(trifluoromethyl)adamantane (CAS 71759-72-3)
- (2S,4S)-1-(tert-butoxycarbonyl)-4-(3,4-difluorophenoxy)pyrrolidine-2-carboxylic acid (CAS 1354486-27-3)
- 1-Methyl-1H-benzo[d]imidazol-7-ol (CAS 163298-76-8)
- 2-Chloro-5-isopropylpyrazine (CAS 1196147-05-3)
- 2,3-Dichloro-5-(difluoromethoxy)benzenesulfonyl chloride (CAS 1804936-65-9)
- Propan-2-amine hydrobromide (CAS 29552-58-7)
- 2-((2,6-Diisopropylphenyl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 723325-66-4)
- N-Butyl-3-iodoaniline (CAS 647035-67-4)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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