2-(4-((4-Bromophenyl)sulfonyl)-1,4-diazepan-1-yl)-4,6-dimethylnicotinonitrile CAS 478256-86-9
| CAS No. | 478256-86-9 |
| Molecular Formula | C19H21BrN4O2S |
| Molecular Weight | 449.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-((4-Bromophenyl)sulfonyl)-1,4-diazepan-1-yl)-4,6-dimethylnicotinonitrile is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-((4-Bromophenyl)sulfonyl)-1,4-diazepan-1-yl)-4,6-dimethylnicotinonitrile (CAS 478256-86-9) is a high-purity analytical reference standard with the molecular formula C19H21BrN4O2S and a molecular weight of 449.36 g/mol.
2-(4-((4-Bromophenyl)sulfonyl)-1,4-diazepan-1-yl)-4,6-dimethylnicotinonitrile (C19H21BrN4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-((4-Bromophenyl)sulfonyl)-1,4-diazepan-1-yl)-4,6-dimethylnicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21BrN4O2S |
| Molecular Weight | 449.36 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Bromophenyl Standards
- 3-(4-(4-Bromophenyl)-5-(cinnamylthio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 477734-67-1)
- 4-(4-(4-Bromophenyl)-5-(cinnamylthio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 477735-11-8)
- 6-{[(4-bromophenyl)sulfanyl]methyl}-2-{[(4-methoxyphenyl)methyl]sulfanyl}pyrimidin-4-ol (CAS 866143-65-9)
- 1-(4-Bromophenyl)-3-(dibenzylamino)pyrrolidine-2,5-dione (CAS 1024631-74-0)
- methyl (1-(2-(4-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate (CAS 1615221-96-9)
- 3-(4-((4-Bromophenyl)sulfonyl)piperazin-1-yl)-6-(1H-imidazol-1-yl)pyridazine (CAS 1396849-66-3)
- 2-{[(E)-{[6-(4-bromophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene}amino]oxy}-1-(morpholin-4-yl)ethan-1-one (CAS 685106-64-3)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-methyl-4-nitrophenyl)acetamide (CAS 332100-78-4)
Recommended Standards
- Ethyl 6-bromo-5-hydroxy-1-methyl-2-((((phenylthio)methyl)amino)methyl)-1H-indole-3-carboxylate (CAS 1704066-66-9)
- Tolcapone 3-O-β-D-glucuronide (CAS 204853-33-8)
- Sitagliptin Impurity 11 (CAS 1379666-94-0)
- Arbidol Impurity 28 (CAS CATO-C4X-112928)
- 4-Formyl-2-methoxyphenyl 2-fluorobenzoate (CAS 380193-74-8)
- N-(Benzo[d]thiazol-2-yl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide (CAS 851131-17-4)
- 3433-37-2 2-Piperidinemethanol Piperidin-2-ylmethanol EINECS 222-333-2 2-Hydroxymethylpiperidine 2-Piperidinylmethanol (CAS 3433-37-2)
- 1-(2,3-difluorophenyl)-1,4-diazepane dihydrochloride (CAS 1820620-30-1)
- Monoerucin (CAS 5389-95-7)
- 4-Chlorothieno[2,3-b]pyridine (CAS 62226-17-9)
- 2-(3,4-Dihydroxyphenyl)ethyl-2,2-d2-amine HCl (CAS 27160-01-6)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(cyclopropyl)methanone (CAS 898762-46-4)
- Tert-butyl 3-((3-iodo-1H-pyrazol-4-yl)methyl)pyrrolidine-1-carboxylate (CAS 2306263-65-8)
- Heptapeptide-6 (CAS CATO-CPTD788823)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com