(E)-3-(dimethylamino)-1-(4-methyl-2-(pyridin-4-yl)thiazol-5-yl)prop-2-en-1-one CAS 478257-67-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-3-(dimethylamino)-1-(4-methyl-2-(pyridin-4-yl)thiazol-5-yl)prop-2-en-1-one.

CATO supplies (E)-3-(dimethylamino)-1-(4-methyl-2-(pyridin-4-yl)thiazol-5-yl)prop-2-en-1-one (CAS 478257-67-9), a certified reference material (molecular formula C14H15N3OS, MW 273.35 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, (E)-3-(dimethylamino)-1-(4-methyl-2-(pyridin-4-yl)thiazol-5-yl)prop-2-en-1-one is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 273.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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