8-[2-(Diphenylmethylidene)hydrazin-1-yl]quinoline CAS 478258-18-3
| CAS No. | 478258-18-3 |
| Molecular Formula | C22H17N3 |
| Molecular Weight | 323.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-[2-(Diphenylmethylidene)hydrazin-1-yl]quinoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 8-[2-(Diphenylmethylidene)hydrazin-1-yl]quinoline (CAS 478258-18-3), a certified reference material (molecular formula C22H17N3, MW 323.39 g/mol) for analytical method development and quality control.
The molecular framework of 8-[2-(Diphenylmethylidene)hydrazin-1-yl]quinoline (C22H17N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H17N3 |
| Molecular Weight | 323.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Diphenylmethylidene Standards
- N'-(Diphenylmethylidene)-2-(pyrrolidin-1-yl)propanehydrazide (CAS 478247-10-8)
- N'-(Diphenylmethylidene)-2-phenoxyacetohydrazide (CAS 320423-94-7)
- N'-(Diphenylmethylidene)-2-(morpholin-4-yl)propanehydrazide (CAS 478247-09-5)
- N'-(Diphenylmethylidene)-2-(pyrrolidin-1-yl)acetohydrazide (CAS 478247-22-2)
- N'-(Diphenylmethylidene)-2-[(prop-2-en-1-yl)amino]acetohydrazide (CAS 341968-06-7)
- N'-(Diphenylmethylidene)-2-(naphthalen-2-yloxy)acetohydrazide (CAS 341967-98-4)
- N'-(Diphenylmethylidene)-2-(4-methyl-2-nitrophenoxy)acetohydrazide (CAS 341967-97-3)
- 1-[(Diphenylmethylidene)amino]cyclopropane-1-carbonitrile (CAS 89985-88-6)
Recommended Standards
- 8-((2,6-Dimethylbenzyl)amino)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylic acid (CAS 816450-73-4)
- Benzyl 2-benzyl-4-oxopiperidine-1-carboxylate (CAS 849928-35-4)
- 7,9-Diamino-N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (CAS 89459-59-6)
- Benzyl 3',4'-dihydro-1'H-spiro[pyrrolidine-3,2'-[1,8]naphthyridine]-1-carboxylate (CAS 2715051-13-9)
- 2-(4-(Benzyloxy)phenyl)-N,N-dimethylacetamide (CAS 919475-15-3)
- (2E)-3-[4-(2-Amino-2-oxoethoxy)-3-methoxyphenyl]-acrylic acid (CAS 696645-32-6)
- (E)-1,2-Difluoro-4-(2-isocyanatovinyl)benzene (CAS 936366-62-0)
- 1-Phenylanthracene (CAS 1714-09-6)
- 4-{[5-(2-chlorophenyl)furan-2-yl]methyl}-1,2-dihydrophthalazin-1-one (CAS 338785-59-4)
- 2'-Amino-6'-(hydroxymethyl)-5-nitro-2,8'-dioxo-8'H-spiro[indoline-3,4'-pyrano[3,2-b]pyran]-3'-carbonitrile (CAS 625376-14-9)
- 1-Cyclopropyl-5-oxopyrrolidine-3-carbaldehyde (CAS 1447958-30-6)
- Phenampromide Hydrochloride (CAS 98348-21-1)
- Methanaminium, N,N'-[2-[(dimethylamino)methylene]-1,3-propanediylidene]bis[N-methyl-, dichloride (CAS 404869-59-6)
- Exenatide (CAS 141758-74-9（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com