5-((1H-indol-1-yl)methyl)-2-chlorothiazole CAS 478258-72-9
| CAS No. | 478258-72-9 |
| Molecular Formula | C12H9ClN2S |
| Molecular Weight | 248.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 5-((1H-indol-1-yl)methyl)-2-chlorothiazole (CAS 478258-72-9), a certified reference material (molecular formula C12H9ClN2S, MW 248.73 g/mol) for analytical method development and quality control.
Structurally, 5-((1H-indol-1-yl)methyl)-2-chlorothiazole (C12H9ClN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 248.73 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN2S |
| Molecular Weight | 248.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related H Standards
- 2-(1H-Indol-3-yl)thiazolidine-4-carboxylic acid (CAS 1182224-95-8)
- 1-((1H-Indol-1-yl)methyl)-1H-benzo[d][1,2,3]triazole (CAS 124337-33-3)
- 3-(1H-Indol-3-yl)isobenzofuran-1(3H)-one (CAS 6936-87-4)
- 3-(1H-Indol-4-yl)imidazo[1,2-a]pyrazin-8-amine (CAS 825630-52-2)
- 4-((1H-Indol-1-yl)methyl)benzimidamide (CAS 83783-25-9)
- 1-(1H-indol-3-yl)-2-phenyl-ethanone (CAS 40281-54-7)
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Recommended Standards
- 4-Methoxy-3-(propan-2-yl)benzene-1-sulfonyl chloride (CAS 627082-12-6)
- 5-ISOPROPYL-2-METHOXYBENZENE-1-SULFONYL CHLORIDE (CAS 88059-65-8)
- 4-isopropoxy-3-methylbenzenesulfonyl chloride (CAS 69129-66-4)
- 6-(4-Chlorophenyl)-3-methylimidazo[2,1-b]thiazole (CAS 25968-22-3)
- tert-Butyl N-[(tert-butoxy)carbonyl]-N-(6-methylpyridin-2-yl)carbamate (CAS 888322-04-1)
- 2,2,3-Tribromobutane (CAS 62127-47-3)
- Ketoconazole Impurity 38 (CAS 24123-68-0)
- 4-Bromo-6-(tert-butyl)-5-methoxy-2-methyl-2,3-dihydro-1H-inden-1-one (CAS 952516-23-3)
- Tert-butyl methyl(3-(thietan-3-ylamino)benzyl)carbamate (CAS 1994538-33-8)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(adamantan-1-yl)acetic acid (CAS 1354546-07-8)
- (1S,3R,4R)-3-[(TERT-BUTOXYCARBONYL)AMINO]-4-[(METHYLSULFONYL)OXY]CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER (CAS 365998-97-6)
- 3-(2-(Benzyloxy)phenyl)isonicotinic acid (CAS 1258632-70-0)
- 2-Chloro-5-((trimethylsilyl)ethynyl)pyridin-4-amine (CAS 1296201-72-3)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
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