2-Chloro-2,2-difluoro-1-(4-hydroxypiperidin-1-yl)ethan-1-one CAS 478258-79-6
| CAS No. | 478258-79-6 |
| Molecular Formula | C7H10ClF2NO2 |
| Molecular Weight | 213.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-2,2-difluoro-1-(4-hydroxypiperidin-1-yl)ethan-1-one (CAS 478258-79-6) is a high-purity analytical reference standard with the molecular formula C7H10ClF2NO2 and a molecular weight of 213.61 g/mol.
The molecular framework of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidin-1-yl)ethan-1-one (C7H10ClF2NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidin-1-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10ClF2NO2 |
| Molecular Weight | 213.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 1-(4-Ethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione (CAS 55383-99-8)
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- 5-(1,3-Benzodioxol-5-ylmethyl)-1,3,4-oxadiazol-2-amine (CAS 14731-90-9)
- N-((5-methylthiazol-2-yl)methyl)cyclopropanamine (CAS 920460-40-8)
- Heptapeptide-6 (CAS CATO-CPTD788823)
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