6-Chloro-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine CAS 478258-94-5
| CAS No. | 478258-94-5 |
| Molecular Formula | C18H17ClN4S |
| Molecular Weight | 356.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine.
6-Chloro-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine (CAS 478258-94-5) is a high-purity analytical reference standard with the molecular formula C18H17ClN4S and a molecular weight of 356.87 g/mol.
Structurally, 6-Chloro-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine (C18H17ClN4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 356.87 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN4S |
| Molecular Weight | 356.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-(2-{6-chloro-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl}thiophen-3-yl)-2,5-dimethyl-1H-pyrrole (CAS 439110-96-0)
- 2-Chloro-1-[4-(5,6,7,8-tetrahydronaphthalene-2-sulfonyl)piperazin-1-yl]ethan-1-one (CAS 929973-02-4)
- 2-Chloro-N-(4,5-di-p-tolylthiazol-2-yl)acetamide (CAS 726157-04-6)
- 2-Chloro-N-(m-tolyl)-N-(4-(p-tolyl)thiazol-2-yl)acetamide (CAS 730951-08-3)
- 21-Chloro-3,6,9,12,15-pentaoxahenicosan-1-ol (CAS 1355956-01-2)
- 4-(4-Chloro-5-(4-methoxyphenyl)oxazol-2-yl)-N,N-diethylaniline (CAS 111961-86-5)
- 4-chloro-N-methyl-N-[(1r,4r)-4-[4-(methylamino)phenyl]cyclohexyl]benzamide (CAS 1797646-62-8)
- 4-Chloro-2-[(2-methyl-1h-indol-3-yl)(morpholin-4-yl)methyl]phenol (CAS 298685-88-8)
Recommended Standards
- 4-[(4-Chlorophenyl)methoxy]-2-methyl-6-[(phenylsulfanyl)methyl]pyrimidine (CAS 339278-72-7)
- N-((2-(4-chlorophenyl)-4-methylthiazol-5-yl)methyl)-4-methylbenzamide (CAS 866018-64-6)
- N-(4-chlorophenyl)-3-(dimethylamino)-4-phenyl-1H-pyrazole-1-carbothioamide (CAS 321553-13-3)
- 1,3,5-tris(bromomethyl)benzene (CAS 18226-42-1)
- tert-butyl N-(4-methyl-2-propyl-1,3-thiazol-5-yl)carbamate (CAS 1797012-32-8)
- 4-[(2,5-dimethylphenyl)thio]aniline hydrochloride (CAS 1049762-40-4)
- Methyl (1S,3S)-3-aminocyclohexane-1-carboxylate (CAS 1461869-65-7)
- (1R,3S)-3-aminocyclopentanecarbonitrile (CAS 1127904-67-9)
- Phthalic Acid, Bis-Isononyl Ester (CAS 68515-48-0)
- 2-(2,2,2-Trifluoroethoxy)benzonitrile (CAS 56935-77-4)
- 1-(5-Bromopyridin-2-yl)azetidin-3-ol (CAS 1339319-85-5)
- [1-(2-chlorophenyl)-1H-1,2,3-triazol-5-yl]methanol (CAS 1429254-44-3)
- Methyl 2-(4-hydroxy-2-oxo-1-(thiophen-2-ylmethyl)-1,2-dihydropyridin-3-yl)acetate (CAS 477858-72-3)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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