2-Chloro-N-(3-chloro-4-methoxybenzyl)-6-nitroaniline CAS 478259-78-8

Purity 97%+In StockPharmaceutical Standards
CAS No.478259-78-8
Molecular FormulaC14H12Cl2N2O3
Molecular Weight327.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-N-(3-chloro-4-methoxybenzyl)-6-nitroaniline CAS 478259-78-8 chemical structure

Description

CATO manufactures 2-Chloro-N-(3-chloro-4-methoxybenzyl)-6-nitroaniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

2-Chloro-N-(3-chloro-4-methoxybenzyl)-6-nitroaniline (CAS 478259-78-8), molecular formula C14H12Cl2N2O3 and molecular weight 327.16 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Chloro-N-(3-chloro-4-methoxybenzyl)-6-nitroaniline (C14H12Cl2N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC14H12Cl2N2O3
Molecular Weight327.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2

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