N-(4-bromo-2-fluorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carbothioamide CAS 478259-97-1
| CAS No. | 478259-97-1 |
| Molecular Formula | C16H13BrFN5O2S |
| Molecular Weight | 438.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, N-(4-bromo-2-fluorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carbothioamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 438.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
N-(4-bromo-2-fluorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carbothioamide (CAS 478259-97-1), molecular formula C16H13BrFN5O2S and molecular weight 438.27 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(4-bromo-2-fluorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carbothioamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13BrFN5O2S |
| Molecular Weight | 438.27 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
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Recommended Standards
- N-(4-Iodo-2-methylphenyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide (CAS 304897-02-7)
- 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-bromobenzoic acid (CAS 2243504-14-3)
- 2-(2-Bromoethoxy)-1-hydroxy-4-(phenylamino)anthracene-9,10-dione (CAS 61556-36-3)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-bromobenzoic acid (CAS 2243505-11-3)
- 2-(4-(Difluoromethyl)-5,6-difluoropyridin-2-yl)acetic acid (CAS 1806017-40-2)
- 1-(4-Benzylphenyl)pentan-1-ol (CAS 1003707-00-3)
- N,N'-DIcyclopentylsulfamide (CAS 31846-23-8)
- Benserazide Impurity 21 (CAS 5625-41-2)
- (1-Phenylethyl)(propyl)amine hydrochloride (CAS 149499-66-1)
- Famotidine Impurity 77 (CAS CATO-C4X-139277)
- Octahydro-1H-isoindole-1-carboxamide (CAS 97039-51-5)
- Methyl 2-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)acetate (CAS 2105139-47-5)
- Posaconazole impurity 224 (CAS CATO-C4X-1208224)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
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