N-{2-[4-(Methylsulfonyl)piperazino]phenyl}-2-thiophenecarboxamide CAS 478260-33-2
| CAS No. | 478260-33-2 |
| Molecular Formula | C16H19N3O3S2 |
| Molecular Weight | 365.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 365.47 g/mol gives N-{2-[4-(Methylsulfonyl)piperazino]phenyl}-2-thiophenecarboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-{2-[4-(Methylsulfonyl)piperazino]phenyl}-2-thiophenecarboxamide (CAS 478260-33-2) is a high-purity analytical reference standard with the molecular formula C16H19N3O3S2 and a molecular weight of 365.47 g/mol.
N-{2-[4-(Methylsulfonyl)piperazino]phenyl}-2-thiophenecarboxamide (C16H19N3O3S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H19N3O3S2 |
| Molecular Weight | 365.47 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related N Standards
- 1-(4-(4-(1-(Methylsulfonyl)azetidine-3-carbonyl)piperazin-1-yl)phenyl)ethan-1-one (CAS 1428364-21-9)
- 1-(Methylsulfonyl)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine (CAS 1428329-80-9)
- 1-(Methylsulfonyl)-N-(4-(pyridin-2-yl)thiazol-2-yl)piperidine-4-carboxamide (CAS 1021265-73-5)
- 1-(Methylsulfonyl)-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)piperazine (CAS 1201644-34-9)
- Ethyl 2-((6-((methylsulfonyl)methyl)-2-(pyridin-2-yl)pyrimidin-4-yl)thio)acetate (CAS 478031-55-9)
- 5-(2-(Methylsulfonyl)phenyl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole (CAS 339015-71-3)
- (((4-(Methylsulfonyl)-1,3-phenylene)bis(oxy))bis(methylene))dibenzene (CAS 1820603-90-4)
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Recommended Standards
- N-{2-[(3-Cyano-4,6-dimethyl-2-pyridinyl)sulfanyl]phenyl}-2-thiophenecarboxamide (CAS 478045-70-4)
- N~3~-(tert-butyl)-N~2~-(4-methylphenyl)-3,4-dihydro-2,3(1H)-isoquinolinedicarboxamide (CAS 318517-14-5)
- N-{1-[(2,6-dimethylphenyl)carbamoyl]cyclohexyl}-N-methylpyridine-3-carboxamide (CAS 503561-73-7)
- tert-Butyl (1-(2-amino-1-(2,5-dimethoxyphenyl)ethyl)pyrrolidin-3-yl)carbamate (CAS 886364-61-0)
- 4-Bromo-2-hydroxy-3-(trifluoromethyl)pyridine (CAS 1227494-15-6)
- Benzyl ((2-methylazetidin-2-yl)methyl)carbamate (CAS 2231675-35-5)
- 2-((tert-Butoxycarbonyl)amino)-3-(1H-indol-4-yl)propanoic acid (CAS 1259997-56-2)
- 2-(Methyl(1-phenylpropyl)amino)acetic acid (CAS 1353955-69-7)
- 2-Bromo-5-chloro-3-(methylthio)pyridine (CAS 1416713-05-7)
- 1-(2-Hydroxyethyl)cyclopentan-1-ol (CAS 73089-93-7)
- Methyl 4-(acridin-9-yl)butanoate (CAS 101733-82-8)
- 1-(2,4-Difluorobenzoyl)-3-methylpiperazine (CAS 1240564-71-9)
- 5-Amino-1H-imidazole-2-carbaldehyde (CAS 1368189-27-8)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
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