(E)-N'-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide CAS 478260-66-1

Purity 97%+In StockPharmaceutical Standards
CAS No.478260-66-1
Molecular FormulaC10H10ClN3S2
Molecular Weight271.79 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-N'-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide CAS 478260-66-1 chemical structure

Description

The occurrence of (E)-N'-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(E)-N'-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide (CAS 478260-66-1), molecular formula C10H10ClN3S2 and molecular weight 271.79 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (E)-N'-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide (C10H10ClN3S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H10ClN3S2
Molecular Weight271.79 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3
Sulfur Atoms2

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