(3Z)-3-{[(4-methylphenyl)methoxy]imino}-1-phenyl-2,3-dihydro-1H-indol-2-one CAS 478261-35-7
| CAS No. | 478261-35-7 |
| Molecular Formula | C22H18N2O2 |
| Molecular Weight | 342.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(3Z)-3-{[(4-methylphenyl)methoxy]imino}-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 478261-35-7), molecular formula C22H18N2O2 and molecular weight 342.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3Z)-3-{[(4-methylphenyl)methoxy]imino}-1-phenyl-2,3-dihydro-1H-indol-2-one (C22H18N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H18N2O2 |
| Molecular Weight | 342.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Z Standards
- n-{1-[(4-methylphenyl)methyl]-1,2-dihydropyridin-2-ylidene}-1h-indazole-3-carboxamide (CAS 1223877-09-5)
- (3E)-3-{[(3-methylphenyl)methoxy]imino}-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 478261-36-8)
- (3Z)-3-{[(2-methylphenyl)methoxy]imino}-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 478261-39-1)
- 1-Methyl-5-{[(4-methylphenyl)sulfanyl]methyl}-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole (CAS 338400-54-7)
- 2-{[(4-methylphenyl)methyl]sulfanyl}-3-propyl-6-(trifluoromethyl)-3,4-dihydropyrimidin-4-one (CAS 860609-26-3)
- 2-{[1-(4-Methylphenyl)-2,5-dioxopyrrolidin-3-yl]thio}nicotinic acid (CAS 838874-00-3)
- 3-[(4-Methylphenyl)sulfanyl]-1-(4-nitrophenyl)pyrrolidine-2,5-dione (CAS 306732-17-2)
- 1-Benzyl-4-[(4-methylphenyl)sulfanyl]phthalazine (CAS 339026-76-5)
Recommended Standards
- (E)-8-Methoxy-2-((naphthalen-1-yloxy)methyl)-8-oxooct-2-enoic acid (CAS 936221-69-1)
- (3Z)-3-[(4-Ethoxyphenyl)imino]-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 303984-68-1)
- (S)-2-(2-((S)-1-(2-Aminoacetyl)pyrrolidine-2-carboxamido)acetamido)-4-methylpentanoic acid (CAS 742068-42-4)
- (3S,4AR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl palmitate (CAS 5973-06-8)
- 5-(4-Chlorophenyl)-1-(2-isopropylphenyl)-3-methyl-1H-pyrazole-4-carboxylic acid (CAS 956743-50-3)
- Reactive Black 5 (CAS 17095-24-8)
- 2-(Chloromethyl)-N,N-diethyl-1,4-dihydro-5-methyl-4-oxothieno[2,3-d]pyrimidine-6-carboxamide (CAS 733030-55-2)
- 2-ethynyl-1-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1638763-51-5)
- 4,4'-((Propane-2,2-diylbis(4,1-phenylene))bis(oxy))diphthalic acid (CAS 38103-05-8)
- Sugammadex Impurity 41 (CAS CATO-C4X-190641)
- 3-(Trifluoromethyl)pyrazole (CAS 20154-03-4)
- Rasagiline Impurity 14 HCl (CAS 200628-33-7)
- 3,5-Difluoro-2-propoxybenzoyl chloride (CAS 1443347-51-0)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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