Ethyl 2-methyl-6-oxo-4-[2-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate CAS 478261-52-8
| CAS No. | 478261-52-8 |
| Molecular Formula | C16H16F3NO3 |
| Molecular Weight | 327.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-methyl-6-oxo-4-[2-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate.
Ethyl 2-methyl-6-oxo-4-[2-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate (CAS 478261-52-8) is a high-purity analytical reference standard with the molecular formula C16H16F3NO3 and a molecular weight of 327.30 g/mol.
Structurally, Ethyl 2-methyl-6-oxo-4-[2-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate (C16H16F3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 327.30 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-methyl-6-oxo-4-[2-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16F3NO3 |
| Molecular Weight | 327.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Ethyl 2-(6-cyclopropyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 938002-48-3)
- Ethyl 5-((tert-butoxycarbonyl)amino)-3-oxo-2-(trifluoromethyl)pentanoate (CAS 2138558-71-9)
- Benzene, 1-bromo-2-(decyloxy)-4-methyl- (CAS 685559-07-3)
- N-(2,4-difluorophenyl)-N-(phenylsulfonyl)glycine (CAS 866049-11-8)
- (2E)-4,4-Dimethoxy-3-methylbut-2-enenitrile (CAS 84586-19-6)
- 2-Chloro-n-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 825630-79-3)
- Vatalanib (CAS 212141-54-3)
- tert-butyl 3-(((2,4-dichloropyrimidin-5-yl)methyl)amino)pyrrolidine-1-carboxylate (CAS 1420841-41-3)
- 2-Amino-4-phosphonobutanoic acid (CAS 6323-99-5)
- (R)-2-Amino-1-(3-(benzyl(isopropyl)amino)pyrrolidin-1-yl)ethanone (CAS 1354004-20-8)
- 2,4-Dichloro-1-(1-chloroethyl)benzene (CAS 60907-89-3)
- tert-butyl N-[2-(5-formyl-1,2-oxazol-3-yl)propan-2-yl]carbamate (CAS 1803595-41-6)
- (S)-2-Amino-4-bromobutanoic acid hydrochloride (CAS 1187453-22-0)
- Tirzepatide Impurity 57 (CAS CATO-C4X-324057)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com