3-Chloro-5-(trifluoromethyl)-N-(2-(5-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethyl)pyridin-2-amine CAS 478262-26-9
| CAS No. | 478262-26-9 |
| Molecular Formula | C16H11ClF6N4 |
| Molecular Weight | 408.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 408.73 g/mol gives 3-Chloro-5-(trifluoromethyl)-N-(2-(5-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethyl)pyridin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Chloro-5-(trifluoromethyl)-N-(2-(5-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethyl)pyridin-2-amine (CAS 478262-26-9), molecular formula C16H11ClF6N4 and molecular weight 408.73 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-5-(trifluoromethyl)-N-(2-(5-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethyl)pyridin-2-amine (C16H11ClF6N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11ClF6N4 |
| Molecular Weight | 408.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 1-(3-Chloro-4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 400079-36-9)
- 4-Chloro-2-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[3,2-c]pyridine (CAS 2792126-10-2)
- (7-Chloro-9,9-dicyclohexyl-9H-fluoren-2-yl)boronic acid (CAS 851119-07-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(3-(trifluoromethyl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 343373-37-5)
- 1-((2-Chloro-4-nitrophenyl)amino)-5-methoxyanthracene-9,10-dione (CAS 62322-92-3)
- 2-Chloro-N-(2-methyl-5-(oxazolo[4,5-b]pyridin-2-yl)phenyl)-5-nitrobenzamide (CAS 309737-80-2)
- 5-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1429906-48-8)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(1H-indol-2-yl)methanone (CAS 634155-07-0)
Recommended Standards
- 2,4-Dichloro-N-(4-((2-chlorophenyl)thio)phenyl)benzamide (CAS 339105-24-7)
- Flufenpyr-ethyl (CAS 188489-07-8)
- Bis(2-ethylhexyl)diphenylsilane (CAS 18759-53-0)
- Di(octan-2-yl)diphenylsilane (CAS 18759-52-9)
- 4-(1-Methyl-1H-pyrazol-5-yl)phenol, 97% (CAS 1206970-50-4)
- 3-Bromo-4-nitrobenzyl chloride (CAS 1260903-11-4)
- n-(1,4-Dihydroxybutan-2-yl)benzamide (CAS 408534-01-0)
- Ochratoxin A-13C20 (CAS CATO-LCFD201910-AL)
- 2-Chloro-3-nitropyridine-4-carboxamide (CAS 1224636-91-2)
- 2-(2,6-Dichloro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121511-76-8)
- 4-Chloro-2-(((1-(4-fluorophenyl)ethyl)amino)methyl)phenol (CAS 1042541-61-6)
- Dimethyl 1-(2-oxopropyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 1039766-69-2)
- Methyl 1-(2,5-difluorobenzyl)piperidine-4-carboxylate (CAS 1057273-55-8)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com