Ethyl 4-(2,4-dichlorophenyl)-2,4-dioxobutanoate CAS 478868-68-7
| CAS No. | 478868-68-7 |
| Molecular Formula | C12H10Cl2O4 |
| Molecular Weight | 289.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 4-(2,4-dichlorophenyl)-2,4-dioxobutanoate (CAS 478868-68-7), molecular formula C12H10Cl2O4 and molecular weight 289.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 4-(2,4-dichlorophenyl)-2,4-dioxobutanoate (C12H10Cl2O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10Cl2O4 |
| Molecular Weight | 289.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Ethyl Standards
- Ethyl 4-(2,5-Dichlorophenyl)-2,4-dioxobutanoate (CAS 1019457-33-0)
- Ethyl 4-(3,4-dichlorophenyl)-2,4-dioxobutanoate (CAS 93618-67-8)
- 7-(2,4-Dichlorophenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 338394-70-0)
- 7-(3,4-Dichlorophenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 320417-13-8)
- 2-((2,5-Dichlorophenyl)amino)-1,3-thiazole-4-carboxylic acid (CAS 1176036-01-3)
- 2-((3,5-Dichlorophenyl)amino)-1,3-thiazole-4-carboxylic acid (CAS 1176121-33-7)
- 1-(2,3-Dichlorophenyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione (CAS 340301-17-9)
- 1-(2,4-Dichlorophenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1h)-one (CAS 340216-38-8)
Recommended Standards
- 8-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one (CAS 2818961-74-7)
- 8-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1(2H)-one (CAS 2818961-87-2)
- N-(2,3-dimethylphenyl)-2-iodoacetamide (CAS 522629-36-3)
- 5-Oxopyrrolidin-3-yl (3,5-dichlorophenyl)carbamate (CAS 88015-96-7)
- 3-(2-Fluoro-5-methylphenyl)aniline, HCl (CAS 1373233-03-4)
- 4,6-Dichloro-1h,2h,3h-pyrrolo[2,3-b]pyridine (CAS 5912-15-2)
- 2-Methyl-N-(2,4,6-trimethoxyphenyl)quinazolin-4-amine (CAS 827031-14-1)
- (5-Bromothiophen-3-yl)methanol (CAS 73919-88-7)
- 4-Iodo-2-(trifluoromethyl)phenol (CAS 1132942-88-1)
- (S)-1-Cbz-3-hydroxypiperidine (CAS 94944-69-1)
- 3-(5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-1-(4-chlorophenyl)prop-2-en-1-one (CAS 648859-49-8)
- 1-Amino-2-methoxy-4-(thiazol-2-ylamino)anthracene-9,10-dione (CAS 62593-07-1)
- Tert-butyl 2-(5-iodopyrimidin-2-yl)pyrrolidine-1-carboxylate (CAS 1817679-13-2)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
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