(E)-7-benzylidene-3-(trifluoromethyl)-3,3a,4,5,6,7-hexahydrobenzo[c]isoxazol-3-ol CAS 479499-03-1
| CAS No. | 479499-03-1 |
| Molecular Formula | C15H14F3NO2 |
| Molecular Weight | 297.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(E)-7-benzylidene-3-(trifluoromethyl)-3,3a,4,5,6,7-hexahydrobenzo[c]isoxazol-3-ol (CAS 479499-03-1), molecular formula C15H14F3NO2 and molecular weight 297.27 g/mol, is a CATO reference standard with documented purity and traceability.
(E)-7-benzylidene-3-(trifluoromethyl)-3,3a,4,5,6,7-hexahydrobenzo[c]isoxazol-3-ol (C15H14F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures (E)-7-benzylidene-3-(trifluoromethyl)-3,3a,4,5,6,7-hexahydrobenzo[c]isoxazol-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H14F3NO2 |
| Molecular Weight | 297.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
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- 3-Benzylidene-5-(3,4-dimethoxyphenyl)-2,3-dihydrofuran (CAS 1171924-23-4)
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Recommended Standards
- (3S,4S)-1-(tert-butoxycarbonyl)-4-(2,2,2-trifluoroethyl)pyrrolidine-3-carboxylic acid (CAS 2089650-63-3)
- 1,2,3,4-Tetrafluoro-7-(methylthio)acridine (CAS 643032-51-3)
- (2R,4S)-1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)piperidine-2-carboxylic acid (CAS 2378490-61-8)
- 1,6-Diamino-4-(4-hydroxy-3-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 354989-31-4)
- 9,9-Di-n-octylfluorene (CAS 123863-99-0)
- 5-(Piperidin-4-yl)isoquinoline (CAS 1256807-40-5)
- [(2,3-Dichlorophenyl)methyl](prop-2-en-1-yl)amine hydrochloride (CAS 1158321-11-9)
- Tetrabutylammonium Cyanide (CAS 10442-39-4)
- N-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)aniline (CAS 142943-95-1)
- 2-Phenyl-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one (CAS 71802-05-6)
- N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)benzamide (CAS 86029-44-9)
- 3-Ethoxy-2-(2-methoxyethyl)-2H-indazole-6-carboxylic acid (CAS 919106-94-8)
- Benserazide impurity 33 (CAS CATO-C4X-142733)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
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