1-Isoindolinone CAS 480-91-1

Purity 97%+In StockPharmaceutical Standards
CAS No.480-91-1
Molecular FormulaC8H7NO
Molecular Weight133.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Isoindolinone CAS 480-91-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 133.15 g/mol gives 1-Isoindolinone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-Isoindolinone (CAS 480-91-1), molecular formula C8H7NO and molecular weight 133.15 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-Isoindolinone (C8H7NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-Isoindolinone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H7NO
Molecular Weight133.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms1

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