(R)-3,3-Dimethyl-1,1-diphenylbutan-2-amine CAS 480444-13-1
| CAS No. | 480444-13-1 |
| Molecular Formula | C18H23N |
| Molecular Weight | 253.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (R)-3,3-Dimethyl-1,1-diphenylbutan-2-amine (CAS 480444-13-1), a certified reference material (molecular formula C18H23N, MW 253.38 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, (R)-3,3-Dimethyl-1,1-diphenylbutan-2-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 253.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H23N |
| Molecular Weight | 253.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related R Standards
- (S)-3,3-Dimethyl-1,1-diphenylbutan-2-amine (CAS 352535-91-2)
- (S)-2,2-dimethyl-1-(3,4,5-trimethoxyphenyl)propan-1-amine (CAS 1388734-64-2)
- (R)-2,2-dimethyl-1-(3,4,5-trimethoxyphenyl)propan-1-amine (CAS 1388854-63-4)
- (2,2-Dimethyl-1,2-dihydroquinolin-4-yl)methanesulfonic acid (CAS 75903-72-9)
- 4-(1',3'-dimethyl-1H,1'H-3,4'-bipyrazol-1-yl)aniline (CAS 1006348-74-8)
- 4-(1',5'-Dimethyl-1h,1'h-[3,4'-bipyrazol]-1-yl)aniline (CAS 1006682-89-8)
- 2-Benzyl-3,4-dimethyl-2H-pyrazolo[3,4-b]pyridin-6(7H)-one (CAS 1018126-53-8)
- 5,6-Dimethyl-7-phenyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine (CAS 106105-24-2)
Recommended Standards
- (R)-(+)-2-amino-4-methyl-1,1-diphenylpentane (CAS 352535-73-0)
- (±)-Naxagolide (CAS 88058-85-9)
- (S)-4-methyl-1,1-diphenylpentan-2-amine (CAS 233772-40-2)
- N-Benzyl-N-butyl-3-methylaniline (CAS 187101-94-6)
- Hexahydro-6-methyl-1H-1,4-Diazepine-1-carboxylic Acid 1,1-Dimethylethyl Ester (CAS 1211595-59-3)
- 2,2,2-Trifluoro-1-(3-(trifluoromethoxy)phenyl)ethan-1-one (CAS 1335013-59-6)
- 1-(2-(2-Methoxyphenoxy)ethyl)-1h-1,2,4-triazole-3-carbonitrile (CAS 1223431-97-7)
- 3-Iodo-5-(phenylthio)-1H-pyrrolo[2,3-b]pyridine (CAS 923583-56-6)
- trans-1-(4-Chlorophenyl)-3-hydroxycyclobutanecarboxylic acid (CAS 1145681-01-1)
- 5-[(1H-1,3-Benzodiazol-2-ylsulfanyl)methyl]-4-phenyl-4H-1,2,4-triazole-3-thiol (CAS 328106-49-6)
- 3-Methyl-[1,3'-biazetidin]-3-ol bis(2,2,2-trifluoroacetate) (CAS 1651840-83-3)
- 4,6-dimethyl-5-methoxyÂ-1-indanone (CAS 109025-37-8)
- ((1R,3r)-3-(aminomethyl)cyclobutyl)methanol (CAS 1609403-60-2)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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