7-Fluoro-2H-chromene-3-carboxylic Acid CAS 480451-09-0

Purity 97%+In StockPharmaceutical Standards
CAS No.480451-09-0
Molecular FormulaC10H7FO3
Molecular Weight194.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Fluoro-2H-chromene-3-carboxylic Acid CAS 480451-09-0 chemical structure

Description

The occurrence of 7-Fluoro-2H-chromene-3-carboxylic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

7-Fluoro-2H-chromene-3-carboxylic Acid (CAS 480451-09-0), molecular formula C10H7FO3 and molecular weight 194.16 g/mol, is a CATO reference standard with documented purity and traceability.

7-Fluoro-2H-chromene-3-carboxylic Acid (C10H7FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-Fluoro-2H-chromene-3-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7FO3
Molecular Weight194.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing

Related Fluoro Standards

Recommended Standards

Why CATO?