Lenalidomide Impurity 4 CAS 48103-74-8
| CAS No. | 48103-74-8 |
| Molecular Formula | C5H7NO3 |
| Molecular Weight | 129.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Lenalidomide Impurity 4 (CAS 48103-74-8) is a certified pharmaceutical impurity reference standard with the molecular formula C5H7NO3 and a molecular weight of 129.11 g/mol.
The molecular framework of Lenalidomide Impurity 4 (C5H7NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H7NO3 |
| Molecular Weight | 129.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1970 |
| Nitrogen Atoms | 1 |
Related Lenalidomide Standards
- Lenalidomide Impurity 48 (CAS 366452-98-4)
- Lenalidomide Impurity 24 (CAS 59434-19-4)
- Lenalidomide Impurity 71 (CAS CATO-C4X-190371)
- Lenalidomide Impurity 70 (CAS CATO-C4X-190370)
- Lenalidomide Impurity 14 (CAS 18583-89-6)
- Lenalidomide Impurity 19 (CAS 366452-97-3)
- Lenalidomide Impurity 26 (CAS 65399-18-0)
- Lenalidomide Impurity 13 (CAS 1975-50-4)
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- Semaglutide Impurity 129 (CAS 2490269-79-7)
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