Diethyl (1,1-difluoro-2-hydroxy-4-phenylbutyl)phosphonate CAS 481053-33-2
| CAS No. | 481053-33-2 |
| Molecular Formula | C14H21F2O4P |
| Molecular Weight | 322.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Diethyl (1,1-difluoro-2-hydroxy-4-phenylbutyl)phosphonate.
CATO supplies Diethyl (1,1-difluoro-2-hydroxy-4-phenylbutyl)phosphonate (CAS 481053-33-2), a certified reference material (molecular formula C14H21F2O4P, MW 322.28 g/mol) for analytical method development and quality control.
The molecular framework of Diethyl (1,1-difluoro-2-hydroxy-4-phenylbutyl)phosphonate (C14H21F2O4P) is characterized by a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Diethyl (1,1-difluoro-2-hydroxy-4-phenylbutyl)phosphonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H21F2O4P |
| Molecular Weight | 322.28 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
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- Ethyl 2,4-dimethylthiophene-3-carboxylate (CAS 36382-81-7)
- (R)-2-Amino-2-[(5-fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate, Trifluoroacetic Acid Salt (CAS 1356019-48-1)
- 2-Hydroxy-5,8-dimethylquinoline-3-carboxylic acid (CAS 436087-34-2)
- 3-(3-Ethoxy-4-(pyridin-4-ylmethoxy)phenyl)acrylic acid (CAS 924871-10-3)
- Ethyl 4-(((1R,4S)-bicyclo[2.2.1]Heptan-2-yl)amino)-2-(methylthio)pyrimidine-5-carboxylate (CAS 1026585-45-4)
- Benzyl (1R,2S)-2-aminocyclobutane-1-carboxylate 2,2,2-trifluoroacetate (CAS 2173637-42-6)
- ((4-Formylphenyl)sulfonyl)glycine (CAS 1239759-16-0)
- (R)-Difluorphos (CAS 503538-69-0)
- Semaglutide impurity 277 (CAS CATO-C4X-2226277)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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