Vitamin K1 Impurity 5 CAS 483-55-6
| CAS No. | 483-55-6 |
| Molecular Formula | C11H8O3 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Vitamin K1 Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Vitamin K1 Impurity 5 (CAS 483-55-6) is a certified pharmaceutical impurity reference standard with the molecular formula C11H8O3 and a molecular weight of 188.18 g/mol.
The molecular framework of Vitamin K1 Impurity 5 (C11H8O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H8O3 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Vitamin Standards
- Vitamin K1 Impurity 30 (CAS 15448-59-6)
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Recommended Standards
- Isosorbide Dinitrate Impurity 5 (CAS 13042-39-2)
- 5-Benzylidenehydantoin (CAS CATO-C4X-214624)
- Isosorbide Dinitrate Impurity 6 (CAS 65940-93-4)
- N-Acetyl-D-Glutamine (CAS 161579-61-9)
- CAS CATO-C4X-34214 (CAS CATO-C4X-34214)
- Dopamine Impurity 80 (CAS CATO-C4X-190880)
- Bilastine impurity 91 (CAS 2245209-60-1)
- 4-(Dichloromethyl)-4-methylcyclohexa-2,5-dien-1-one (CAS 6611-78-5)
- 4-[(2,4-Dichlorophenoxy)methyl]-1-[(4-methylphenyl)sulfanyl]-2-nitrobenzene (CAS 477869-64-0)
- (R)-Aminofol D3 (CAS 1286597-21-4)
- Formoterol Impurity 56 (CAS 333796-54-6)
- 3-((tert-Butoxycarbonyl)amino)-4-chloro-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 2580248-53-7)
- 6-Ethyl-5-methylpyrimidine-2,4(1H,3H)-dione (CAS 32796-82-0)
- Insulin Detemir (CAS 169148-63-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com