2-[[3,4-Dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]thio]acetic acid CAS 483350-66-9

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

2-[[3,4-Dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]thio]acetic acid (CAS 483350-66-9), molecular formula C17H14N2O3S and molecular weight 326.37 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-[[3,4-Dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]thio]acetic acid (C17H14N2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

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