Tert-butyl (S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate CAS 483366-14-9

Purity 97%+In StockPharmaceutical Standards
CAS No.483366-14-9
Molecular FormulaC10H14F2N2O2
Molecular Weight232.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl (S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate CAS 483366-14-9 chemical structure

Description

The molecular framework of Tert-butyl (S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate (C10H14F2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

CATO supplies Tert-butyl (S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate (CAS 483366-14-9), a certified reference material (molecular formula C10H14F2N2O2, MW 232.23 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Tert-butyl (S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H14F2N2O2
Molecular Weight232.23 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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