1-(Isopropylsulfonyl)piperidin-4-amine hydrochloride CAS 483366-19-4
| CAS No. | 483366-19-4 |
| Molecular Formula | C8H18N2O2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Isopropylsulfonyl)piperidin-4-amine hydrochloride (CAS 483366-19-4) is a high-purity analytical reference standard with the molecular formula C8H18N2O2SHCl and a molecular weight of 242.76 g/mol.
The molecular framework of 1-(Isopropylsulfonyl)piperidin-4-amine hydrochloride (C8H18N2O2SHCl) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(Isopropylsulfonyl)piperidin-4-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H18N2O2S HCl |
| Molecular Weight | 242.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Isopropylsulfonyl Standards
- Isopropylsulfonyl chloride (CAS 10147-37-2)
- 4-((Isopropylsulfonyl)methyl)piperidine (CAS 1018533-19-1)
- 2-(Isopropylsulfonyl)aniline hydrochloride (CAS 1022968-46-2)
- 1-(Isopropylsulfonyl)piperazine hydrochloride (CAS 1062059-60-2)
- [4-(Isopropylsulfonyl)phenyl]acetic acid (CAS 1105193-73-4)
- 5-[3-(Isopropylsulfonyl)phenyl]-1,3,4-oxadiazol-2-amine (CAS 1105194-09-9)
- 1-(4-(4-(2-(Isopropylsulfonyl)phenylamino)-1H-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol (CAS 1125593-20-5)
- [4-(Isopropylsulfonyl)phenyl]acetyl chloride (CAS 1170402-71-7)
Recommended Standards
- 5-Bromo-6-chloroquinoline (CAS 16560-60-4)
- N-(2-Bromophenyl)piperidine-4-carboxamide (CAS 951381-76-3)
- (4-Bromo-1,2-thiazol-5-yl)methanamine (CAS 1781571-44-5)
- 6-Bromo-2-chloro-3-iodo-4-methylpyridine (CAS 1823934-07-1)
- 2-(2,6-Difluoro-benzoylamino)-3-methyl-butyric acid (CAS 1396972-19-2)
- Ethyl 2,4,6-triisopropylbenzoate (CAS 63846-76-4)
- T2HIT6N5UF 2009-83-8 6-Chloro-1-hexanol 6-Chlorohexan-1-ol 1-Hexanol, 6-chloro- 4-01-00-01704 (Beilstein Handbook Reference) AI3-61541 BRN 1697307 omega-Chlorohexanol 1-Chloro-6-hexanol 6-Chlorohexanol EINECS 217-925-2 Hexamethylene chlorohydrin NSC 3700 UNII-T2HIT6N5UF EC 217-925-2 (CAS 2009-83-8)
- 6-Nitro-1-naphthoic acid (CAS 1975-45-7)
- (4-Amino-3-cyano-2-(trifluoromethyl)quinolin-6-yl)boronic acid (CAS 1315335-66-0)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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