2,3,4,5,6-Pentamethylbenzyl Chloride CAS 484-65-1
| CAS No. | 484-65-1 |
| Molecular Formula | C12H17Cl |
| Molecular Weight | 196.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,3,4,5,6-Pentamethylbenzyl Chloride.
2,3,4,5,6-Pentamethylbenzyl Chloride (CAS 484-65-1) is a high-purity analytical reference standard with the molecular formula C12H17Cl and a molecular weight of 196.72 g/mol.
The molecular framework of 2,3,4,5,6-Pentamethylbenzyl Chloride (C12H17Cl) is characterized by chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17Cl |
| Molecular Weight | 196.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Pentamethylbenzyl Standards
- 5-((2,3,4,5,6-Pentamethylbenzyl)thio)-1,3,4-thiadiazol-2-amine (CAS 882079-12-1)
- 3-Ethyl-2-((2,3,4,5,6-pentamethylbenzyl)thio)quinazolin-4(3H)-one (CAS 882082-87-3)
- 4-Oxo-2-((2,3,4,5,6-pentamethylbenzyl)thio)-4-(p-tolyl)butanoic acid (CAS 868255-47-4)
- 2-((2,3,4,5,6-Pentamethylbenzyl)thio)-3-phenylquinazolin-4(3H)-one (CAS 329079-90-5)
Recommended Standards
- 1-Chloro-3,5-di(propan-2-yl)benzene (CAS 87945-06-0)
- 4-(tert-Butyl)-2-(chloromethyl)-1-methylbenzene (CAS 23203-13-6)
- (6-Chlorohexyl)benzene (CAS 71434-68-9)
- 1-(Chloromethyl)-4-(tert-pentyl)benzene (CAS 28162-11-0)
- 1,4,5-Trihydroxy-8-((2-hydroxyethyl)amino)anthracene-9,10-dione (CAS 83249-33-6)
- Ethyl 2-(3-iodobenzoyl)benzoate (CAS 890098-39-2)
- (5-Nitrofuran-2-yl)methyl 2-bromoacetate (CAS 6281-24-9)
- 8-Bromo-6-methylindolizine-2-carbonitrile (CAS 1474057-49-2)
- (4-(4,6-Diphenyl-1,3,5-triazin-2-yl)phenyl)boronic acid (CAS 1313018-07-3)
- 5-(Azetidin-3-yl)pyridin-3-amine (CAS 1260859-63-9)
- n-((1h-Indol-4-yl)methyl)-2-methoxyethan-1-amine (CAS 944896-86-0)
- 2,4-Dichloro-5-iodoquinazoline (CAS 959237-30-0)
- (E)-2-((4-chlorophenyl)thio)-1-(6-methylthiazolo[3,2-b][1,2,4]triazol-5-yl)ethan-1-one O-isopropyl oxime (CAS 866131-17-1)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
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