N-(2,5-dimethoxyphenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide CAS 486456-95-5
| CAS No. | 486456-95-5 |
| Molecular Formula | C20H24FN3O3 |
| Molecular Weight | 373.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-(2,5-dimethoxyphenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 486456-95-5), a certified reference material (molecular formula C20H24FN3O3, MW 373.42 g/mol) for analytical method development and quality control.
N-(2,5-dimethoxyphenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (C20H24FN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24FN3O3 |
| Molecular Weight | 373.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-(2,5-dimethoxyphenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide (CAS 491867-73-3)
- 5-(2-(3,4-Dimethoxyphenyl)propan-2-yl)-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol (CAS 1239964-46-5)
- 6-((2,3-Dimethoxyphenyl)(morpholino)methyl)benzo[d][1,3]dioxol-5-ol (CAS 102616-64-8)
- (R)-(2,3-Dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol (CAS 139290-65-6)
- (2,3-Dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol (CAS 139290-69-0)
- 2-(3,4-Dimethoxyphenyl)ethyl N-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbamate (CAS 320423-06-1)
- 2-(2-(2-(3,4-Dimethoxyphenyl)acetyl)-4,5-dimethoxyphenyl)acetic acid (CAS 26954-85-8)
- 1-(2,5-Dimethoxyphenyl)-2-{[5-(3-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethan-1-one (CAS 459845-67-1)
Recommended Standards
- N-(3-acetyl-2,6-dimethylbenzofuran-5-yl)-4-methoxybenzenesulfonamide (CAS 848335-57-9)
- N-(2,4-Difluorophenyl)-2-((2,2-dimethyl-5-phenyl-2H-imidazol-4-yl)thio)acetamide (CAS 899934-52-2)
- N-Boc-3-(p-toluenesulfonyloxy)-L-serine methyl ester (CAS 56926-94-4)
- Methyl 3-[(cyclopropylcarbonyl)amino]-4-[(4-methylphenyl)sulfonyl]benzenecarboxylate (CAS 477858-88-1)
- (S)-2-Benzyl-3,3-difluoropyrrolidine (CAS 1786411-01-5)
- 2-Ethoxy-5-formylbenzoic acid (CAS 848606-43-9)
- Ethyl 6-Chloroimidazo[1,2-b]pyridazine-3-carboxylate (CAS 1150566-27-0)
- 1-{3-[(3,5-Dihydroxyphenyl)methyl]azetidin-1-yl}ethan-1-one (CAS 1801243-46-8)
- 3-Chloro-2-(4-ethylphenoxy)aniline (CAS 946682-42-4)
- 7-Boc-2,4-dichloro-5,6,8,9-tetrahydropyrimido[4,5-d]azepine (CAS 1065114-27-3)
- 3,4-Dichloro-N-(2-hydroxyphenyl)benzene-1-sulfonamide (CAS 881302-41-6)
- 3-([1,1'-Biphenyl]-3-ylmethyl)piperazin-2-one (CAS 1260640-55-8)
- 3-Fluoro-4-methoxyphenylacetonitrile (CAS 404-90-0)
- Semaglutide impurity 277 (CAS CATO-C4X-2226277)
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