3-Ethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride CAS 486460-18-8
| CAS No. | 486460-18-8 |
| Molecular Formula | C7H12N4 |
| Molecular Weight | 152.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Ethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride.
3-Ethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride (CAS 486460-18-8) is a high-purity analytical reference standard with the molecular formula C7H12N4 and a molecular weight of 152.20 g/mol.
Structurally, 3-Ethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride (C7H12N4) contains a nitrile group, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 152.20 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Ethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H12N4 |
| Molecular Weight | 152.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Ethyl Standards
- 6,7,8,9-Tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-9-amine (CAS 1019258-80-0)
- 3-Methyl-6,7,8,9-tetrahydro-5h-[1,2,4]triazolo[4,3-d][1,4]diazepine (CAS 1083274-19-4)
- 3-Methyl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a][1,4]diazepine (CAS 1260666-51-0)
- 2-Methyl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[1,5-a][1,4]diazepine (CAS 1260669-84-8)
- 3-Methyl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a][1,3]diazepine (CAS 1365969-24-9)
- (5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-6-yl)methanamine (CAS 1375474-67-1)
- 1-Methyl-4,5,6,7-tetrahydro-1H-benzo[d][1,2,3]triazol-6-amine (CAS 1487952-37-3)
- 1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1553231-55-2)
Recommended Standards
- 3-(Pyrrolidin-1-ylmethyl)-1H-1,2,4-triazole (CAS 657349-21-8)
- 3H-imidazo[4,5-b]pyridine-7-carbonitrile (CAS 78316-13-9)
- 3-(4H-1,2,4-triazol-3-yl)piperidine (CAS 933750-46-0)
- 3-Methyl-1,2,3,7-tetrahydropyrazolo[1,5-a]pyrimidin-6-amine (CAS 439902-01-9)
- RKI-1447 (CAS 1342278-01-6)
- 1-Benzoylazetidine-3-carboxylic acid (CAS 97639-63-9)
- (2S,3S)-3-(Benzyloxy)butane-1,2,4-triol (CAS 84379-51-1)
- 1-Benzoylpyrrolidine-2,5-dione (CAS 6343-27-7)
- Vildagliptin Impurity 111 (CAS CATO-C4X-1100111)
- 2-(1-(Furan-2-yl)prop-1-en-2-yl)-2,3-dihydro-1H-perimidine (CAS 315230-90-1)
- 4-(3,4-Dimethoxybenzylidene)-2-methyloxazol-5(4H)-one (CAS 41888-65-7)
- 3-Pyrimidin-2-yl-propan-1-ol (CAS 260441-09-6)
- 3-Amino-1H-pyrrolo[2,3-c]pyridine-7-carboxylic acid (CAS 1190310-11-2)
- Neuropeptide Y, human (CAS 98264-90-5)
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