3-Chloro-5-[(4-chlorophenyl)methanesulfinyl]-1,2,4-thiadiazole CAS 486997-65-3
| CAS No. | 486997-65-3 |
| Molecular Formula | C9H6Cl2N2OS2 |
| Molecular Weight | 293.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-5-[(4-chlorophenyl)methanesulfinyl]-1,2,4-thiadiazole.
3-Chloro-5-[(4-chlorophenyl)methanesulfinyl]-1,2,4-thiadiazole (CAS 486997-65-3) is a high-purity analytical reference standard with the molecular formula C9H6Cl2N2OS2 and a molecular weight of 293.19 g/mol.
The molecular framework of 3-Chloro-5-[(4-chlorophenyl)methanesulfinyl]-1,2,4-thiadiazole (C9H6Cl2N2OS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Chloro-5-[(4-chlorophenyl)methanesulfinyl]-1,2,4-thiadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6Cl2N2OS2 |
| Molecular Weight | 293.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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