4-(2,4-Difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid CAS 487057-91-0
| CAS No. | 487057-91-0 |
| Molecular Formula | C13H11F2NO3 |
| Molecular Weight | 267.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2,4-Difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(2,4-Difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid (CAS 487057-91-0), molecular formula C13H11F2NO3 and molecular weight 267.23 g/mol, is a CATO reference standard with documented purity and traceability.
4-(2,4-Difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid (C13H11F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2,4-Difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11F2NO3 |
| Molecular Weight | 267.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenyl Standards
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- 1-(3,4-Difluorophenyl)-5-propyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1097117-88-8)
- Ethyl 3-(2,3-difluorophenyl)-5-methylisoxazole-4-carboxylate (CAS 1159602-35-3)
- Ethyl 3-(2,5-difluorophenyl)-5-methylisoxazole-4-carboxylate (CAS 1159602-54-6)
- Methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate (CAS 1902955-29-6)
- 4-{[(2,4-difluorophenyl)amino]methylidene}-3-(methoxymethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 240799-65-9)
- Ethyl 3-(3,4-difluorophenyl)-5-methylisoxazole-4-carboxylate (CAS 917388-46-6)
Recommended Standards
- 3-(Bromo(phenyl)methylene)isoindolin-1-one (CAS 5194-49-0)
- 4-(Methoxycarbonyl)-2-(pyrrolidine-1-carbonyl)furan-3-carboxylic acid (CAS 5165-13-9)
- 2-Nitro Iso-apiole (CAS 22959-13-3)
- 4-(Methoxycarbonyl)-5-(pyrrolidine-1-carbonyl)furan-3-carboxylic acid (CAS 50347-44-9)
- Tetradecyl acrylate (CAS 21643-42-5)
- 5,6-Dibromo-2,3-dihydro-isoindol-1-one (CAS 954239-43-1)
- 2H-chromen-2-amine (CAS 67747-72-2)
- 5-Chloro-1-ethyl-1h-pyrazole-4-sulfonyl chloride (CAS 1427022-70-5)
- tert-Butyl (3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (CAS 1256360-04-9)
- N-(2,4-Dichlorophenyl)-5-methylisoxazole-4-carboxamide (CAS 61669-26-9)
- trans-4-[2-Oxo-2-(3-trifluoromethylphenyl)-ethyl]cyclohexane-1-carboxylic acid (CAS 736136-63-3)
- ZK756326 (CAS 874911-96-3)
- 4-Oxo-6,7,8,9-tetrahydro-4H-pyrazino[1,2-a]pyrimidine-3-carbonitrile (CAS 2092038-14-5)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
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