Methyl 5-methoxy-2-methyl-1H-indole-3-carboxylate CAS 4871-80-1
| CAS No. | 4871-80-1 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 5-methoxy-2-methyl-1H-indole-3-carboxylate (CAS 4871-80-1) is a high-purity analytical reference standard with the molecular formula C12H13NO3 and a molecular weight of 219.24 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Methyl 5-methoxy-2-methyl-1H-indole-3-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-methoxy-2-methyl-1H-indole-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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- 5-Methoxy-1,2-dimethyl-1H-indole-3-carboxylic acid (CAS 105909-93-1)
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Recommended Standards
- methyl 5-hydroxy-1,2-dimethyl-1H-indole-3-carboxylate (CAS 73975-59-4)
- Methyl 5-methoxy-3-methyl-1H-indole-2-carboxylate (CAS 480996-91-6)
- Methyl 5-cyano-6-(dimethylamino)-2-methylnicotinate (CAS 860649-57-6)
- Methyl 5-Methoxyindole-3-acetate (CAS 23304-48-5)
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- 2-((3,5-Dimethylphenyl)amino)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1197556-76-5)
- (R)-3-Amino-4-(tert-Butoxy)butanoic Acid (CAS 1956437-97-0)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(3,5-bis(trifluoromethyl)benzyl)propanoic acid (CAS 1260613-53-3)
- 4-{[2,4-Di(tert-butyl)phenoxy]methyl}piperidinehydrochloride (CAS 1220021-32-8)
- 1242925-85-4 1-Ethyl-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indole MFCD15732285 (CAS 1242925-85-4)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
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