5-Chloro-2-cyclopropyl-1H-benzimidazole CAS 4887-92-7
| CAS No. | 4887-92-7 |
| Molecular Formula | C10H9ClN2 |
| Molecular Weight | 192.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chloro-2-cyclopropyl-1H-benzimidazole (CAS 4887-92-7), a certified reference material (molecular formula C10H9ClN2, MW 192.64 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 5-Chloro-2-cyclopropyl-1H-benzimidazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-2-cyclopropyl-1H-benzimidazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN2 |
| Molecular Weight | 192.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-chloro-2-cyclopropyl-1H-Pyrrolo[2,3-b]pyridine (CAS 1014613-52-5)
- 7-Chloro-2-methylquinolin-8-amine (CAS 102876-99-3)
- 5-Chloro-2-methylquinolin-8-amine (CAS 102879-01-6)
- 1-Chloro-4-methoxynaphthalene (CAS 10443-43-3)
- 3-Chloro-4-(1H-pyrrol-1-yl)aniline (CAS 106981-50-4)
- 6-Chloro-3-(prop-1-en-2-yl)imidazo[1,2-a]pyridine (CAS 1080429-96-4)
- 2-chloro-5,7-dimethyl-1,6-naphthyridine (CAS 1085267-44-2)
- 1-Chloro-6-methylisoquinolin-5-amine (CAS 1093101-44-0)
Recommended Standards
- 5-Chloro-1-methyl-3-phenyl-1H-pyrazole (CAS 59803-60-0)
- 5-chloro-2-ethyl-1,6-naphthyridine (CAS 2528154-94-9)
- 5-Chloro-1-methyl-2-phenyl-1H-imidazole (CAS 7666-52-6)
- 5-chloro-2-methyl-3-nitro-aniline (CAS 219312-44-4)
- 2-(2-(1,3-Dioxolan-2-yl)phenyl)pyridine (CAS 150711-15-2)
- N-((2-Methoxyadamantan-2-yl)methyl)cyclobutanecarboxamide (CAS 1797727-16-2)
- 1-Bromo-3-(chloromethoxy)benzene (CAS 1520745-74-7)
- 2-(2,4-Dimethylphenoxy)acetonitrile (CAS 43111-35-9)
- (S)-10-Amino-3-(benzyloxy)-2-methoxy-7,12-dihydrobenzo[5,6][1,4]diazepino[1,2-b]isoquinoline-6,14(5H,6aH)-dione (CAS 1964489-92-6)
- 1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-methylprop-2-en-1-one (CAS 300709-89-1)
- 444989-46-2 3-Chloro-4-(tributylstannyl)-pyridine MFCD22370076 (CAS 444989-46-2)
- 3-(4-Ethoxyphenyl)-2-(methylthio)-3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one (CAS 536710-25-5)
- 2-(2-Acetyl-4-chlorophenoxy)-N-isopropylacetamide (CAS 923106-52-9)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com