2-Chloro-2-methylbenzophenone CAS 4888-03-3
| CAS No. | 4888-03-3 |
| Molecular Formula | C14H13ClO |
| Molecular Weight | 232.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Chloro-2-methylbenzophenone (CAS 4888-03-3), molecular formula C14H13ClO and molecular weight 232.71 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-2-methylbenzophenone (C14H13ClO) contains a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 2-Chloro-2-methylbenzophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13ClO |
| Molecular Weight | 232.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
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Recommended Standards
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- Ribavirin Impurity 37 (CAS CATO-C4X-141337)
- 2-(3-(N-Ethylacetamido)pyrrolidin-1-yl)acetic acid (CAS 1353946-48-1)
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- 2-Methyl-2-(4-methylpiperidin-1-yl)propan-1-amine 3580AF 933724-18-6 C10H22N2 (CAS 933724-18-6)
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