2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-2-phenylacetic acid CAS 488827-01-6
| CAS No. | 488827-01-6 |
| Molecular Formula | C25H23F3N2O2S |
| Molecular Weight | 472.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-2-phenylacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-2-phenylacetic acid (CAS 488827-01-6) is a high-purity analytical reference standard with the molecular formula C25H23F3N2O2S and a molecular weight of 472.52 g/mol.
The molecular framework of 2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-2-phenylacetic acid (C25H23F3N2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H23F3N2O2S |
| Molecular Weight | 472.52 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Adamantan Standards
- N-(Adamantan-1-yl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydroquinoline-3-carboxamide (CAS 1048039-15-1)
- Ethyl (2-((6-(adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)acetyl)carbamate (CAS 625376-59-2)
- (4S)-4-(Adamantan-1-yl)-2-(2-(diphenylphosphanyl)phenyl)-4,5-dihydrooxazole (CAS 944836-03-7)
- 2-((6-(Adamantan-1-yl)-3-cyanopyridin-2-yl)thio)-N-(3,4-dimethoxyphenyl)acetamide (CAS 371127-15-0)
- 1-(2-(Di(adamantan-1-yl)phosphino)phenyl)piperidine (CAS 1237588-13-4)
- N-(Adamantan-1-yl)-2-{[6-(adamantan-1-yl)-3-cyanopyridin-2-yl]sulfanyl}acetamide (CAS 330852-25-0)
- 2-(4-(Adamantan-1-yl)thiazol-2-yl)-3-oxo-4-(4-phenylpiperazin-1-yl)butanenitrile (CAS 868269-74-3)
- 2-((6-(Adamantan-1-yl)-3-cyanopyridin-2-yl)thio)-N-(benzo[d]thiazol-2-yl)acetamide (CAS 313379-93-0)
Recommended Standards
- 4-Bromo-N-(2-chloro-4-iodophenyl)benzenesulfonamide (CAS 1406294-50-5)
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- N-(5-(bis(2-methoxyethyl)amino)-2-((5-nitrobenzo[c]isothiazol-3-yl)diazenyl)phenyl)acetamide (CAS 105076-77-5)
- Cefazolin Impurity 12 (CAS CATO-C4X-157712)
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- 5-Bromo-8-chloro-1,2,3,4-tetrahydroisoquinoline (CAS 1445948-16-2)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(2,4-diphenyl-1,3-thiazol-5-yl)methyl]-1,3,4-oxadiazole (CAS 338401-66-4)
- 6,7-Dichloro-3H-imidazo[4,5-b]pyridine (CAS 1378594-79-6)
- 2-(4-(Methylamino)piperidin-1-yl)acetic acid hydrochloride (CAS 1624260-55-4)
- 4-(3-Ethylureido)-3-methoxyphenylboronic acid pinacol ester, 97% (CAS 917111-46-7)
- 2-((6-Chloro-4-(trifluoromethyl)pyridin-2-yl)thio)ethan-1-ol (CAS 188591-51-7)
- Tert-butyl hexahydropyrrolo[3,4-b][1,4]oxazine-4(4aH)-carboxylate (CAS 1367907-47-8)
- Semaglutide impurity 235 (CAS CATO-C4X-2226235)
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